Fracture and Bone Mineral Density Response by Baseline Risk in Patients Treated With Abaloparatide Followed by Alendronate: Results From the Phase 3 ACTIVExtend Trial
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DOI: 10.1002/jbmr.3848
Abstract: In the randomized, placebo‐controlled, double‐blind phase 3 ACTIVE study (NCT01343004), 18 months of abaloparatide 80 μg daily (subcutaneous injection) in postmenopausal women at risk of osteoporotic fracture significantly reduced the risk of vertebral, nonvertebral, clinical, and major… read more here.
Keywords: risk; bone mineral; fracture; baseline risk ... See more keywords
Baseline risk characterization of early versus later adopters of long‐acting paliperidone palmitate formulations
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DOI: 10.1002/npr2.12260
Abstract: Early Post‐Marketing Phase Vigilance (EPPV) is a unique system that encourages reporting of serious adverse reactions for medications newly introduced to Japan. When a once‐monthly paliperidone palmitate formulation (PP1M) was introduced in Japan in 2013,… read more here.
Keywords: baseline risk; paliperidone palmitate; mortality; risk ... See more keywords
Differences in baseline risk estimated by physicians and patients with early breast cancer.
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DOI: 10.1093/jjco/hyab152
Abstract: BACKGROUND Physicians recommend adjuvant therapy to patients based on baseline risk. A common recognition for baseline risk between patients and physicians is critical for successful adjuvant therapy. We prospectively investigated the differences in estimated baseline… read more here.
Keywords: risk; differences estimated; estimated baseline; baseline risk ... See more keywords
Statins for the primary prevention of cardiovascular disease: an overview of systematic reviews
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DOI: 10.1136/bmjopen-2018-023085
Abstract: Objective To synthesise evidence from exclusively primary prevention data on the effectiveness of statins for prevention of cardiovascular disease (CVD), including stroke, and outcomes stratified by baseline risk and gender. Design Overview of systematic reviews… read more here.
Keywords: risk; baseline risk; systematic reviews; primary prevention ... See more keywords