Baseline and time-updated factors in preclinical development of anionic dendrimers as successful anti-HIV-1 vaginal microbicides.
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DOI: 10.1002/wnan.1774
Abstract: Although a wide variety of topical microbicides provide promising in vitro and in vivo efficacy, most of them failed to prevent sexual transmission of human immunodeficiency virus type 1 (HIV-1) in human clinical trials. In… read more here.
Keywords: development; baseline time; clinical trials; preclinical development ... See more keywords