Leopard Spots in Antiglomerular Basement Membrane Disease.
Sign Up to like & getrecommendations! Published in 2025 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2025.1865
Abstract: This case report discusses a diagnosis of Goodpasture syndrome in a patient aged 56 years who presented with 4 months of blurred vision and bilateral leopard spots on fundus examination. read more here.
Keywords: leopard spots; basement membrane; spots antiglomerular; ophthalmology ... See more keywords
Quantitative Characterization of Undulation Patterns and Regional Features of the Oral Basement Membrane Zone Using Optical Coherence Tomography
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Biophotonics"
DOI: 10.1002/jbio.202500252
Abstract: Alterations in the undulation pattern of the basement membrane zone (BMZ) reflect early pathological changes in oral squamous cell carcinoma (OSCC). Optical coherence tomography (OCT) provides real‐time, high‐resolution, in vivo three‐dimensional (3D) imaging of the… read more here.
Keywords: optical coherence; basement membrane; membrane zone; undulation ... See more keywords
Quantitative Assessment of Basement Membrane Loss in Melasma Using Attenuation Coefficient Estimation Based on Optical Coherence Tomography.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of biophotonics"
DOI: 10.1002/jbio.202500491
Abstract: Melasma is a common pigmentary disorder involving melanin deposition and structural alterations. Current diagnostic methods mainly target pigmentation and lack real-time assessment of histopathology. This study proposes a noninvasive, quantitative evaluation of basement membrane (BM)… read more here.
Keywords: melasma; attenuation coefficient; optical coherence; basement membrane ... See more keywords
Enhanced structure and function of human pluripotent stem cell‐derived beta‐cells cultured on extracellular matrix
Sign Up to like & getrecommendations! Published in 2020 at "Stem Cells Translational Medicine"
DOI: 10.1002/sctm.20-0224
Abstract: The differentiation of human stem cells into insulin secreting beta‐like cells holds great promise to treat diabetes. Current protocols drive stem cells through stages of directed differentiation and maturation and produce cells that secrete insulin… read more here.
Keywords: stem; basement membrane; cell; beta cells ... See more keywords
Basement membrane defects in CD151-associated glomerular disease
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric Nephrology"
DOI: 10.1007/s00467-022-05447-y
Abstract: CD151 is a cell-surface molecule of the tetraspanin family. Its lateral interaction with laminin-binding integrin ɑ3β1 is important for podocyte adhesion to the glomerular basement membrane (GBM). Deletion of Cd151 in mice induces glomerular dysfunction,… read more here.
Keywords: cd151; microscopy; disease; cd151 associated ... See more keywords
Surface patterning of protein matrix basement by thermal imprinting
Sign Up to like & getrecommendations! Published in 2017 at "Microsystem Technologies"
DOI: 10.1007/s00542-016-2815-5
Abstract: In order to hourly monitor the variation of specific cell growth, a grid mesh for the recording of adhesion positions on the surface of glass slides and dishes is printed. However, since the focal length… read more here.
Keywords: thermal imprinting; basement membrane; basement; protein matrix ... See more keywords
Pathologic glomerular characteristics and glomerular basement membrane alterations in biopsy-proven thin basement membrane nephropathy
Sign Up to like & getrecommendations! Published in 2018 at "Clinical and Experimental Nephrology"
DOI: 10.1007/s10157-018-01687-1
Abstract: BackgroundThin basement membrane nephropathy (TBMN) is diagnosed by diffuse thinning of the glomerular basement membrane (GBM) without any clinical and pathologic findings of Alport syndrome and the other renal diseases. TBMN is characterized clinically by… read more here.
Keywords: membrane nephropathy; basement membrane; basement; biopsy proven ... See more keywords
Glomerular filtration and podocyte tensional homeostasis: importance of the minor type IV collagen network.
Sign Up to like & getrecommendations! Published in 2020 at "Biomechanics and modeling in mechanobiology"
DOI: 10.1007/s10237-020-01347-y
Abstract: The minor type IV collagen chain, which is a significant component of the glomerular basement membrane in healthy individuals, is known to assemble into large structures (supercoils) that may contribute to the mechanical stability of… read more here.
Keywords: collagen; minor chain; network; filtration ... See more keywords
Notch regulates vascular collagen IV basement membrane through modulation of lysyl hydroxylase 3 trafficking
Sign Up to like & getrecommendations! Published in 2021 at "Angiogenesis"
DOI: 10.1007/s10456-021-09791-9
Abstract: Collagen type IV (Col IV) is a basement membrane protein associated with early blood vessel morphogenesis and is essential for blood vessel stability. Defects in vascular Col IV deposition are the basis of heritable disorders,… read more here.
Keywords: col; basement membrane; secretion; blood vessel ... See more keywords
Supportive properties of basement membrane layer of human amniotic membrane enable development of tissue engineering applications
Sign Up to like & getrecommendations! Published in 2017 at "Cell and Tissue Banking"
DOI: 10.1007/s10561-017-9680-z
Abstract: Human amniotic membrane (HAM) has been widely used as a natural scaffold in tissue engineering due to many of its unique biological properties such as providing growth factors, cytokines and tissue inhibitors of metalloproteinases. This… read more here.
Keywords: amniotic membrane; microscopy; basement membrane; tissue ... See more keywords
Effects of aging on protein expression in mice brain microvessels: ROS scavengers, mRNA/protein stability, glycolytic enzymes, mitochondrial complexes, and basement membrane components.
Sign Up to like & getrecommendations! Published in 2021 at "GeroScience"
DOI: 10.1007/s11357-021-00468-1
Abstract: Differentially expressed (DE) proteins in the cortical microvessels (MVs) of young, middle-aged, and old male and female mice were evaluated using discovery-based proteomics analysis (> 4,200 quantified proteins/group). Most DE proteins (> 90%) showed no significant differences… read more here.
Keywords: old mice; mrna protein; basement membrane; protein stability ... See more keywords