Enhanced structure and function of human pluripotent stem cell‐derived beta‐cells cultured on extracellular matrix
Sign Up to like & getrecommendations! Published in 2020 at "Stem Cells Translational Medicine"
DOI: 10.1002/sctm.20-0224
Abstract: The differentiation of human stem cells into insulin secreting beta‐like cells holds great promise to treat diabetes. Current protocols drive stem cells through stages of directed differentiation and maturation and produce cells that secrete insulin… read more here.
Keywords: stem; basement membrane; cell; beta cells ... See more keywords
Basement membrane defects in CD151-associated glomerular disease
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric Nephrology"
DOI: 10.1007/s00467-022-05447-y
Abstract: CD151 is a cell-surface molecule of the tetraspanin family. Its lateral interaction with laminin-binding integrin ɑ3β1 is important for podocyte adhesion to the glomerular basement membrane (GBM). Deletion of Cd151 in mice induces glomerular dysfunction,… read more here.
Keywords: cd151; microscopy; disease; cd151 associated ... See more keywords
Surface patterning of protein matrix basement by thermal imprinting
Sign Up to like & getrecommendations! Published in 2017 at "Microsystem Technologies"
DOI: 10.1007/s00542-016-2815-5
Abstract: In order to hourly monitor the variation of specific cell growth, a grid mesh for the recording of adhesion positions on the surface of glass slides and dishes is printed. However, since the focal length… read more here.
Keywords: thermal imprinting; basement membrane; basement; protein matrix ... See more keywords
Pathologic glomerular characteristics and glomerular basement membrane alterations in biopsy-proven thin basement membrane nephropathy
Sign Up to like & getrecommendations! Published in 2018 at "Clinical and Experimental Nephrology"
DOI: 10.1007/s10157-018-01687-1
Abstract: BackgroundThin basement membrane nephropathy (TBMN) is diagnosed by diffuse thinning of the glomerular basement membrane (GBM) without any clinical and pathologic findings of Alport syndrome and the other renal diseases. TBMN is characterized clinically by… read more here.
Keywords: membrane nephropathy; basement membrane; basement; biopsy proven ... See more keywords
Glomerular filtration and podocyte tensional homeostasis: importance of the minor type IV collagen network.
Sign Up to like & getrecommendations! Published in 2020 at "Biomechanics and modeling in mechanobiology"
DOI: 10.1007/s10237-020-01347-y
Abstract: The minor type IV collagen chain, which is a significant component of the glomerular basement membrane in healthy individuals, is known to assemble into large structures (supercoils) that may contribute to the mechanical stability of… read more here.
Keywords: collagen; minor chain; network; filtration ... See more keywords
Notch regulates vascular collagen IV basement membrane through modulation of lysyl hydroxylase 3 trafficking
Sign Up to like & getrecommendations! Published in 2021 at "Angiogenesis"
DOI: 10.1007/s10456-021-09791-9
Abstract: Collagen type IV (Col IV) is a basement membrane protein associated with early blood vessel morphogenesis and is essential for blood vessel stability. Defects in vascular Col IV deposition are the basis of heritable disorders,… read more here.
Keywords: col; basement membrane; secretion; blood vessel ... See more keywords
Supportive properties of basement membrane layer of human amniotic membrane enable development of tissue engineering applications
Sign Up to like & getrecommendations! Published in 2017 at "Cell and Tissue Banking"
DOI: 10.1007/s10561-017-9680-z
Abstract: Human amniotic membrane (HAM) has been widely used as a natural scaffold in tissue engineering due to many of its unique biological properties such as providing growth factors, cytokines and tissue inhibitors of metalloproteinases. This… read more here.
Keywords: amniotic membrane; microscopy; basement membrane; tissue ... See more keywords
Effects of aging on protein expression in mice brain microvessels: ROS scavengers, mRNA/protein stability, glycolytic enzymes, mitochondrial complexes, and basement membrane components.
Sign Up to like & getrecommendations! Published in 2021 at "GeroScience"
DOI: 10.1007/s11357-021-00468-1
Abstract: Differentially expressed (DE) proteins in the cortical microvessels (MVs) of young, middle-aged, and old male and female mice were evaluated using discovery-based proteomics analysis (> 4,200 quantified proteins/group). Most DE proteins (> 90%) showed no significant differences… read more here.
Keywords: old mice; mrna protein; basement membrane; protein stability ... See more keywords
Idiopathic Pulmonary Hemosiderosis as a Mimic of Pulmonary Vasculitis: A Case Report and Review of the Literature
Sign Up to like & getrecommendations! Published in 2020 at "Current Allergy and Asthma Reports"
DOI: 10.1007/s11882-020-00907-7
Abstract: Purpose of Review Idiopathic pulmonary hemosiderosis (IPH) is one of the rarest and least understood causes of pulmonary hemorrhage in children. Illustrated by a complex case presentation, we discuss the clinical manifestations, diagnosis, pathology, proposed… read more here.
Keywords: pulmonary hemosiderosis; idiopathic pulmonary; basement membrane; disease ... See more keywords
Clinicopathological characteristics of typical and atypical anti-glomerular basement membrane nephritis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Nephrology"
DOI: 10.1007/s40620-017-0394-x
Abstract: Anti-glomerular basement membrane (GBM) antibody disease is a rare pathological condition that mainly involves renal and/or pulmonary parenchyma. It is characterized by the presence of circulating anti-GBM antibodies accompanied by a linear deposition of immunoglobulins… read more here.
Keywords: glomerular basement; anti gbm; anti glomerular; basement membrane ... See more keywords
Implementation of a basement membrane invasion assay using mesenteric tissue.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in cell biology"
DOI: 10.1016/bs.mcb.2019.10.001
Abstract: Metastasis accounts for nearly 90% of all cancer associated mortalities. A hallmark of metastasis in malignancies of epithelial origin such as in the pancreas and breast, is invasion of the basement membrane (BM). While various… read more here.
Keywords: invasion; basement membrane; invasion assay; mesenteric tissue ... See more keywords