Critical comparison of shake‐flask, potentiometric and chromatographic methods for lipophilicity evaluation (log Po/w) of neutral, acidic, basic, amphoteric, and zwitterionic drugs
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DOI: 10.1016/j.ejps.2018.07.010
Abstract: &NA; In the present study three different procedures have been compared for the determination of the lipophilicity of the unionized species (log Po/w) of neutral, acidic, basic, amphoteric, and zwitterionic drugs. Shake‐flask, potentiometric and chromatographic… read more here.
Keywords: amphoteric zwitterionic; acidic basic; basic amphoteric; log neutral ... See more keywords