Structure-activity relationships studies on weakly basic N-arylsulfonylindoles with an antagonistic profile in the 5-HT 6 receptor
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DOI: 10.1016/j.molstruc.2017.03.067
Abstract: Abstract We recently reported a series of 39 weakly basic N -arylsulfonylindoles as novel 5-HT 6 antagonists. Eight of the compounds exhibited moderate to high binding affinities, with 2-(4-(2-Methoxyphenyl)piperazin-1-yl)-1-(1-tosyl-1 H -indol-3-yl)ethanol 16 showing the highest… read more here.
Keywords: activity relationships; structure activity; weakly basic; basic arylsulfonylindoles ... See more keywords