A basic charge cluster near the C-terminus of the cytoplasmic tail contributes to the molecular stability of human herpesvirus 8 E3 ubiquitin ligases.
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DOI: 10.1111/1348-0421.13068
Abstract: Human herpesvirus 8 (HHV8; also known as Kaposi's sarcoma‐associated herpesvirus [KSHV]) utilizes the viral E3 ubiquitin ligase family members K3 and K5 for immune evasion. Both K3 and K5 mediate the ubiquitination of host MHC… read more here.
Keywords: cytoplasmic tail; tail; charge cluster; basic charge ... See more keywords