Developing a Formulation Strategy Coupled with PBPK Modeling and Simulation for the Weakly Basic Drug Albendazole
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DOI: 10.3390/pharmaceutics15041040
Abstract: Albendazole (ABZ) is a weakly basic drug that undergoes extensive presystemic metabolism after oral administration and converts to its active form albendazole sulfoxide (ABZ_SO). The absorption of albendazole is limited by poor aqueous solubility, and… read more here.
Keywords: formulation; pbpk modeling; basic drug; abz ... See more keywords