Vitamin D basis of Alzheimer’s disease: from genetics to biomarkers
Sign Up to like & getrecommendations! Published in 2018 at "Hormones"
DOI: 10.1007/s42000-018-0086-5
Abstract: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder seen mostly in the elderly population. While to date AD research has focused on either neurochemical disruptions, genetic studies, or the pathological hallmarks, little has been done… read more here.
Keywords: research; alzheimer disease; genetics; disease ... See more keywords
Structural basis of Alzheimer β-amyloid peptide recognition by engineered lipocalin proteins with aggregation-blocking activity
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DOI: 10.1515/hsz-2021-0375
Abstract: Abstract We describe the structural analysis of two Anticalin® proteins that tightly bind Aβ40, a peptide involved in the pathophysiology of Alzheimer’s disease. These anticalins, US7 and H1GA, were engineered on the basis of the… read more here.
Keywords: alzheimer amyloid; amyloid peptide; structural basis; alzheimer ... See more keywords