Structural Basis of Functional Transitions in Mammalian NMDA Receptors
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DOI: 10.1016/j.cell.2020.05.052
Abstract: Excitatory neurotransmission meditated by glutamate receptors including N-methyl-D-aspartate receptors (NMDARs) is pivotal to brain development and function. NMDARs are heterotetramers composed of GluN1 and GluN2 subunits, which bind glycine and glutamate, respectively, to activate their… read more here.
Keywords: structural basis; transitions mammalian; inhibition; functional transitions ... See more keywords
Molecular basis for functional diversity among microbial Nep1-like proteins
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DOI: 10.1371/journal.ppat.1007951
Abstract: Necrosis and ethylene-inducing peptide 1 (Nep1)-like proteins (NLPs) are secreted by several phytopathogenic microorganisms. They trigger necrosis in various eudicot plants upon binding to plant sphingolipid glycosylinositol phosphorylceramides (GIPC). Interestingly, HaNLP3 from the obligate biotroph… read more here.
Keywords: like proteins; nep1 like; molecular basis; toxic nlps ... See more keywords
Structural Basis for the Functional Diversity of Centrins: A Focus on Calcium Sensing Properties and Target Recognition
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DOI: 10.3390/ijms222212173
Abstract: Centrins are a family of small, EF hand-containing proteins that are found in all eukaryotes and are often complexed with centrosome-related structures. Since their discovery, centrins have attracted increasing interest due to their multiple, diverse… read more here.
Keywords: structural basis; functional diversity; ca2; basis functional ... See more keywords