Structural basis of purine nucleotide inhibition of human uncoupling protein 1.
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DOI: 10.1126/sciadv.adh4251
Abstract: Mitochondrial uncoupling protein 1 (UCP1) gives brown adipose tissue of mammals its specialized ability to burn calories as heat for thermoregulation. When activated by fatty acids, UCP1 catalyzes the leak of protons across the mitochondrial… read more here.
Keywords: uncoupling protein; purine; structural basis; basis purine ... See more keywords