Structural Basis for Selectivity and Diversity in Angiotensin II Receptors
Sign Up to like & getrecommendations! Published in 2017 at "Nature"
DOI: 10.1038/nature22035
Abstract: The angiotensin II receptors AT1R and AT2R serve as key components of the renin–angiotensin–aldosterone system. AT1R has a central role in the regulation of blood pressure, but the function of AT2R is unclear and it… read more here.
Keywords: basis selectivity; angiotensin receptors; structural basis; selectivity ... See more keywords
The structural basis for the selectivity of sulfonamido dicarbaboranes toward cancer-associated carbonic anhydrase IX
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Enzyme Inhibition and Medicinal Chemistry"
DOI: 10.1080/14756366.2020.1816996
Abstract: Abstract Human carbonic anhydrase IX (CA IX), a protein specifically expressed on the surface of solid tumour cells, represents a validated target both for anticancer therapy and diagnostics. We recently identified sulfonamide dicarbaboranes as promising… read more here.
Keywords: basis selectivity; structural basis; carbonic anhydrase; dicarbaborane cluster ... See more keywords