Structural Basis of Sirtuin 6-Catalyzed Nucleosome Deacetylation.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c13512
Abstract: The reversible acetylation of histone lysine residues is controlled by the action of acetyltransferases and deacetylases (HDACs), which regulate chromatin structure and gene expression. The sirtuins are a family of NAD-dependent HDAC enzymes, and one… read more here.
Keywords: deacetylation; histone; sirt6; structural basis ... See more keywords