Basophil Activation Techniques: Staining of Exteriorized Granule Matrix.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0696-4_17
Abstract: The basis of traditional flow cytometry allergy diagnosis is measurement of the expression of basophilic surface activation and/or degranulation markers. Basophils, upon encounter with a specific allergen that cross-links surface FcRI-bound IgE antibodies, not only… read more here.
Keywords: basophil activation; granule matrix; staining exteriorized;
Basophil Activation Test: Old and New Applications in Allergy
Sign Up to like & getrecommendations! Published in 2018 at "Current Allergy and Asthma Reports"
DOI: 10.1007/s11882-018-0831-5
Abstract: Purpose of ReviewThe basophil activation test (BAT) using flow cytometry has supplanted traditional methods of measuring basophil degranulation using histamine and other mediator release, and can be used for clinical applications as well as to… read more here.
Keywords: basophil activation; bat; activation test; response ... See more keywords
Relevance of the basophil activation test in a cohort of 240 patients with chronic spontaneous urticaria.
Sign Up to like & getrecommendations! Published in 2024 at "Clinical and experimental dermatology"
DOI: 10.1093/ced/llae441
Abstract: BACKGROUND Basophil activation test (BAT) is considered to be the best biomarker to predict autoimmune chronic spontaneous urticaria (aiCSU). To date, few studies have investigated the utility of BAT in real-life clinical practice, the role… read more here.
Keywords: cohort; basophil activation; bat; test ... See more keywords
Adhesion molecule cross‐linking and cytokine exposure modulate IgE‐ and non‐IgE‐dependent basophil activation
Sign Up to like & getrecommendations! Published in 2020 at "Immunology"
DOI: 10.1111/imm.13268
Abstract: Basophils are known for their role in allergic inflammation, which makes them suitable targets in allergy diagnostics such as the basophil activation test (BAT) and the microfluidic immunoaffinity basophil activation test (miBAT). Beside their role… read more here.
Keywords: ige; adhesion; basophil activation; cross linking ... See more keywords
Exploring the role of basophil activation test in diagnosis of Dermatophagoides farinae sensitization and evaluation of therapeutic efficacy of subcutaneous immunotherapy in children
Sign Up to like & getrecommendations! Published in 2022 at "Scandinavian Journal of Immunology"
DOI: 10.1111/sji.13168
Abstract: It aims to detect basophil activation ratio (%CD63+) in peripheral blood of children with allergic asthma and rhinitis by using flow cytometry (FCM), so as to analyse the application values and clinical relevance of the… read more here.
Keywords: basophil activation; diagnosis; sensitization; derf sensitization ... See more keywords
Immunoglobulin (Ig)G antibodies against IgE identified by basophil activation test as the putative causative agent of a serious allergic transfusion reaction: potential utility of the test as a new safety measure for allergic transfusion reactions
Sign Up to like & getrecommendations! Published in 2018 at "Transfusion"
DOI: 10.1111/trf.14878
Abstract: In most cases of allergic transfusion reactions (ATRs), the causative agents have not been identified and the mechanisms are largely unknown, with a few exceptions. The basophil activation test (BAT) was recently introduced in the… read more here.
Keywords: allergic transfusion; activation test; basophil activation; transfusion ... See more keywords
Basophil activation test for allergic and febrile non‐haemolytic transfusion reactions among paediatric patients with haematological or oncological disease
Sign Up to like & getrecommendations! Published in 2022 at "Vox Sanguinis"
DOI: 10.1111/vox.13365
Abstract: Allergic transfusion reactions (ATRs) and febrile non‐haemolytic transfusion reactions (FNHTRs) are common, although their mechanisms remain unclear. Immunoglobulin E (IgE)‐mediated type I hypersensitivity may be involved in the pathogenesis of ATR. A basophil activation test… read more here.
Keywords: haemolytic transfusion; basophil activation; febrile non; non haemolytic ... See more keywords
Abstract 5793: Measurement of basophil activation using a flow cytometry method for applications in clinical research and clinical trials
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-5793
Abstract: Basophils are a type of white blood cell that play a role in the immune system, particularly in defending the body against allergens, pathogens, and parasites. Basophils also can contribute to the immune response directed… read more here.
Keywords: activation; basophil activation; research; flow cytometry ... See more keywords
Basophil activation in insect venom allergy: comparison of an established test using liquid reagents with a test using 5-color tubes with dried antibody reagents
Sign Up to like & getrecommendations! Published in 2024 at "BMC Immunology"
DOI: 10.1186/s12865-024-00616-0
Abstract: Background Flow cytometry-based basophil activation tests (BAT) have been performed with various modifications, differing in the use of distinct identification and activation markers. Established tests use liquid reagents while a new development involves the use… read more here.
Keywords: basophil activation; activation; bat; insect venom ... See more keywords
Immediate allergic reaction to thiocolchicoside confirmed by skin testing and basophil activation test: A case report and literature review.
Sign Up to like & getrecommendations! Published in 2021 at "Asian Pacific journal of allergy and immunology"
DOI: 10.12932/ap-250320-0793
Abstract: BACKGROUND Thiocolchicoside is a muscle relaxant, anti-inflammatory, and analgesic. Administered orally, intramuscularly, or topically, this drug is used in the symptomatic treatment of muscular spasms and rheumatologic disorders. Despite its extensive use, thiocolchicoside is a… read more here.
Keywords: activation test; basophil activation; reaction thiocolchicoside;
Effect of brimonidine tartrate on basophil activation in glaucoma patients.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of ophthalmology"
DOI: 10.18240/ijo.2020.03.21
Abstract: AIM To evaluate the mechanism of which brimonidine tartrate 0.15% causes clinical hypersensitivity. METHODS A prospective case-control study comparing 8 glaucoma patients with clinical hypersensitivity to brimonidine to a control group consisting 13 healthy volunteers.… read more here.
Keywords: basophil activation; brimonidine tartrate; activation; brimonidine ... See more keywords