Basophil Activation Techniques: Staining of Exteriorized Granule Matrix.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0696-4_17
Abstract: The basis of traditional flow cytometry allergy diagnosis is measurement of the expression of basophilic surface activation and/or degranulation markers. Basophils, upon encounter with a specific allergen that cross-links surface FcRI-bound IgE antibodies, not only… read more here.
Keywords: basophil activation; granule matrix; staining exteriorized;
Basophil Activation Test: Old and New Applications in Allergy
Sign Up to like & getrecommendations! Published in 2018 at "Current Allergy and Asthma Reports"
DOI: 10.1007/s11882-018-0831-5
Abstract: Purpose of ReviewThe basophil activation test (BAT) using flow cytometry has supplanted traditional methods of measuring basophil degranulation using histamine and other mediator release, and can be used for clinical applications as well as to… read more here.
Keywords: basophil activation; bat; activation test; response ... See more keywords
Adhesion molecule cross‐linking and cytokine exposure modulate IgE‐ and non‐IgE‐dependent basophil activation
Sign Up to like & getrecommendations! Published in 2020 at "Immunology"
DOI: 10.1111/imm.13268
Abstract: Basophils are known for their role in allergic inflammation, which makes them suitable targets in allergy diagnostics such as the basophil activation test (BAT) and the microfluidic immunoaffinity basophil activation test (miBAT). Beside their role… read more here.
Keywords: ige; adhesion; basophil activation; cross linking ... See more keywords
Exploring the role of basophil activation test in diagnosis of Dermatophagoides farinae sensitization and evaluation of therapeutic efficacy of subcutaneous immunotherapy in children
Sign Up to like & getrecommendations! Published in 2022 at "Scandinavian Journal of Immunology"
DOI: 10.1111/sji.13168
Abstract: It aims to detect basophil activation ratio (%CD63+) in peripheral blood of children with allergic asthma and rhinitis by using flow cytometry (FCM), so as to analyse the application values and clinical relevance of the… read more here.
Keywords: basophil activation; diagnosis; sensitization; derf sensitization ... See more keywords
Immunoglobulin (Ig)G antibodies against IgE identified by basophil activation test as the putative causative agent of a serious allergic transfusion reaction: potential utility of the test as a new safety measure for allergic transfusion reactions
Sign Up to like & getrecommendations! Published in 2018 at "Transfusion"
DOI: 10.1111/trf.14878
Abstract: In most cases of allergic transfusion reactions (ATRs), the causative agents have not been identified and the mechanisms are largely unknown, with a few exceptions. The basophil activation test (BAT) was recently introduced in the… read more here.
Keywords: allergic transfusion; activation test; basophil activation; transfusion ... See more keywords
Basophil activation test for allergic and febrile non‐haemolytic transfusion reactions among paediatric patients with haematological or oncological disease
Sign Up to like & getrecommendations! Published in 2022 at "Vox Sanguinis"
DOI: 10.1111/vox.13365
Abstract: Allergic transfusion reactions (ATRs) and febrile non‐haemolytic transfusion reactions (FNHTRs) are common, although their mechanisms remain unclear. Immunoglobulin E (IgE)‐mediated type I hypersensitivity may be involved in the pathogenesis of ATR. A basophil activation test… read more here.
Keywords: haemolytic transfusion; basophil activation; febrile non; non haemolytic ... See more keywords
Immediate allergic reaction to thiocolchicoside confirmed by skin testing and basophil activation test: A case report and literature review.
Sign Up to like & getrecommendations! Published in 2021 at "Asian Pacific journal of allergy and immunology"
DOI: 10.12932/ap-250320-0793
Abstract: BACKGROUND Thiocolchicoside is a muscle relaxant, anti-inflammatory, and analgesic. Administered orally, intramuscularly, or topically, this drug is used in the symptomatic treatment of muscular spasms and rheumatologic disorders. Despite its extensive use, thiocolchicoside is a… read more here.
Keywords: activation test; basophil activation; reaction thiocolchicoside;
Effect of brimonidine tartrate on basophil activation in glaucoma patients.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of ophthalmology"
DOI: 10.18240/ijo.2020.03.21
Abstract: AIM To evaluate the mechanism of which brimonidine tartrate 0.15% causes clinical hypersensitivity. METHODS A prospective case-control study comparing 8 glaucoma patients with clinical hypersensitivity to brimonidine to a control group consisting 13 healthy volunteers.… read more here.
Keywords: basophil activation; brimonidine tartrate; activation; brimonidine ... See more keywords
AMG853, A Bispecific Prostaglandin D2 Receptor 1 and 2 Antagonist, Dampens Basophil Activation and Related Lupus-Like Nephritis Activity in Lyn-Deficient Mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.824686
Abstract: Systemic lupus erythematosus is a complex autoimmune disease during which patients develop autoantibodies raised against nuclear antigens. During the course of the disease, by accumulating in secondary lymphoid organs (SLOs), basophils support autoreactive plasma cells… read more here.
Keywords: ptgdr ptgdr; basophil activation; disease; lupus like ... See more keywords
Basophil Activation Test with Different Polyethylene Glycols in Patients with Suspected PEG Hypersensitivity Reactions
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232314592
Abstract: Allergic reactions to COVID-19 vaccine components are rare but should be considered. Polyethylene glycol (PEG) is responsible for anaphylaxis in mRNA vaccines. Skin tests have been used in the allergological work-up programs for COVID-19 vaccine… read more here.
Keywords: activation test; basophil activation; polyethylene; test ... See more keywords
Basophil Activation Test in the Diagnosis of Anisakis Allergy: An Observational Study from an Area of High Seafood Consumption in Italy
Sign Up to like & getrecommendations! Published in 2023 at "Pathogens"
DOI: 10.3390/pathogens12060777
Abstract: The rising popularity of undercooked or raw seafood containing larvae of the Anisakis parasite has led to issues of public health concern due to allergic manifestations. We conducted an observational study on the use of… read more here.
Keywords: anisakis allergy; activation test; basophil activation; seafood ... See more keywords