Stereocontrolled Total Synthesis of Bastimolide B Using Iterative Homologation of Boronic Esters
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DOI: 10.1021/jacs.2c03192
Abstract: Bastimolide B is a polyhydroxy macrolide isolated from marine cyanobacteria displaying antimalarial activity. It features a dense array of hydroxylated stereogenic centers with 1,5-relationships along a hydrocarbon chain. These 1,5-polyols represent a particularly challenging motif… read more here.
Keywords: synthesis bastimolide; synthesis; bastimolide using; stereocontrolled total ... See more keywords