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   Articles with "bat thermogenesis" as a keyword



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Human Brown Adipocyte Thermogenesis Is Driven by β2-AR Stimulation.

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recommendations! Published in 2020 at "Cell metabolism"

DOI: 10.1016/j.cmet.2020.07.005

Abstract: Stimulation of brown adipose tissue (BAT) thermogenesis in humans has emerged as an attractive target to improve metabolic health. Pharmacological stimulations targeting the β3-adrenergic receptor (β3-AR), the adrenergic receptor believed to mediate BAT thermogenesis, have… read more here.

Keywords: brown adipocyte; stimulation; bat thermogenesis; adipocyte thermogenesis ... See more keywords
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Role of APPL1 in BAT thermogenesis.

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recommendations! Published in 2019 at "Metabolism: clinical and experimental"

DOI: 10.1016/j.metabol.2019.153955

Abstract: OBJECTIVES The activation of brown adipose tissue (BAT) is considered as a promising therapeutic target for obesity. APPL1 (Adaptor protein containing the Pleckstrin homology domain, Phosphotyrosine binding domain and Leucine zipper motif) is an intracellular… read more here.

Keywords: appl1 bat; bat; bat thermogenesis; role ... See more keywords
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High Fat Diet Suppresses Energy Expenditure Via Neurons in the Brainstem

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recommendations! Published in 2023 at "Neuroscience"

DOI: 10.2139/ssrn.4185820

Abstract: Oxidation of fat by brown adipose tissue (BAT) contributes to energy balance and heat production. During cold exposure, BAT thermogenesis produces heat to warm the body. Obese subjects and rodents, however, show impaired BAT thermogenesis… read more here.

Keywords: bat thermogenesis; energy; bat; high fat ... See more keywords
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The crosstalk between BAT thermogenesis and skeletal muscle dysfunction

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recommendations! Published in 2023 at "Frontiers in Physiology"

DOI: 10.3389/fphys.2023.1132830

Abstract: Metabolic defects increase the risk of skeletal muscle diseases, and muscle impairment might worsen metabolic disruption, leading to a vicious cycle. Both brown adipose tissue (BAT) and skeletal muscle play important roles in non-shivering thermogenesis… read more here.

Keywords: bat thermogenesis; muscle; bat; skeletal muscle ... See more keywords
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Increased BAT Thermogenesis in Male Mouse Apolipoprotein A4 Transgenic Mice

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recommendations! Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24044231

Abstract: Dietary lipids induce apolipoprotein A4 (APOA4) production and brown adipose tissue (BAT) thermogenesis. Administration of exogenous APOA4 elevates BAT thermogenesis in chow-fed mice, but not high-fat diet (HFD)-fed mice. Chronic feeding of HFD attenuates plasma… read more here.

Keywords: bat thermogenesis; hfd; apoa4; bat ... See more keywords
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MiR-22 modulates brown adipocyte thermogenesis by synergistically activating the glycolytic and mTORC1 signaling pathways

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recommendations! Published in 2021 at "Theranostics"

DOI: 10.7150/thno.50900

Abstract: Background: Brown adipose tissue (BAT) dissipates chemical energy as heat and has the potential to be a protective strategy to prevent obesity. microRNAs (miRNAs) are emerging as important posttranscriptional factors affecting the thermogenic function of… read more here.

Keywords: mtorc1 signaling; bat; bat thermogenesis; mir modulates ... See more keywords