Prevalence and Mechanisms of Carbapenem Resistance Among Acinetobacter baumannii Clinical Isolates in Egypt.
Sign Up to like & getrecommendations! Published in 2019 at "Microbial drug resistance"
DOI: 10.1089/mdr.2018.0141
Abstract: The increasing number of carbapenem-resistant Acinetobacter baumannii clinical isolates is a major concern, which restricts therapeutic options for treatment of serious infections caused by this emerging pathogen. The aim of this work is to assess… read more here.
Keywords: carbapenem resistance; resistance; clinical isolates; baumannii clinical ... See more keywords
The Low-Alkalinity Polymyxin Derivative, AL-6, Shows High Activity Against Multidrug-Resistant Acinetobacter baumannii Clinical Isolates In Vitro and A. baumannii ATCC 19606 In Vivo: Preliminary Analysis of the Antibacterial Mechanism.
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DOI: 10.1089/mdr.2019.0474
Abstract: Polymyxin B and colistin (polymyxin E) are increasingly used as the last line of therapy for infections caused by multidrug-resistant (MDR) gram-negative pathogens. However, nephrotoxicity is still a limiting factor for the use of polymyxin.… read more here.
Keywords: polymyxin; clinical isolates; baumannii clinical; activity ... See more keywords
Co‐evolutionary adaptations of Acinetobacter baumannii and a clinical carbapenemase‐encoding plasmid during carbapenem exposure
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DOI: 10.1111/eva.13441
Abstract: OXA‐23 is the predominant carbapenemase in carbapenem‐resistant Acinetobacter baumannii. The co‐evolutionary dynamics of A. baumannii and OXA‐23‐encoding plasmids are poorly understood. Here, we transformed A. baumannii ATCC 17978 with pAZJ221, a blaOXA−23‐containing plasmid from clinical… read more here.
Keywords: carbapenem; blaoxa; acinetobacter baumannii; pazj221 ... See more keywords
Incidence of an Intracellular Multiplication Niche among Acinetobacter baumannii Clinical Isolates
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DOI: 10.1128/msystems.00488-21
Abstract: Multidrug-resistant Acinetobacter baumannii isolates are associated with significant morbidity and mortality in hospitals worldwide. Understanding their pathogenicity is critical for improving therapeutic management. ABSTRACT The spread of antibiotic-resistant Acinetobacter baumannii poses a significant threat to… read more here.
Keywords: clinical isolates; microscopy; multiplication; acinetobacter baumannii ... See more keywords
Adjuvant antimicrobial activity and resensitization efficacy of geraniol in combination with antibiotics on Acinetobacter baumannii clinical isolates
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DOI: 10.1371/journal.pone.0271516
Abstract: Adjuvant use of geraniol, a plant essential oil component, is known to increase the efficacy of antibiotics by acting as a potent inhibitor of efflux mechanisms. In this study, we assessed the effect of a… read more here.
Keywords: clinical isolates; antimicrobial activity; efficacy; adjuvant antimicrobial ... See more keywords
Genomic Determinants of Pathogenicity and Antimicrobial Resistance of Nosocomial Acinetobacter baumannii Clinical Isolates of Hospitalized Patients (2019–2021) from a Sentinel Hospital in Hangzhou, China
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DOI: 10.2147/idr.s407577
Abstract: Purpose Acinetobacter baumannii (A. baumannii or AB) is one of the most opportunistic, nosocomial pathogens threatening public healthcare across countries. A. baumannii has become a primary growing concern due to its exceptional ability to acquire… read more here.
Keywords: clinical isolates; hospitalized patients; acinetobacter baumannii; resistance ... See more keywords
The Prevalence of Virulence Factor Genes among Carbapenem-Non-Susceptible Acinetobacter baumannii Clinical Strains and Their Usefulness as Potential Molecular Biomarkers of Infection
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DOI: 10.3390/diagnostics13061036
Abstract: Healthcare-associated infections caused by multidrug-resistant Acinetobacter baumannii strains are a serious global threat. Therefore, it is important to expand the knowledge on the mechanisms of pathogenicity of these particular bacteria. The aim of this study… read more here.
Keywords: non susceptible; clinical strains; virulence; baumannii clinical ... See more keywords