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Published in 2023 at "Journal of Medicinal Chemistry"
DOI: 10.1021/acs.jmedchem.2c01597
Abstract: We have developed compounds with a promising activity against Acinetobacter baumannii and Pseudomonas aeruginosa, which are both on the WHO priority list of antibiotic-resistant bacteria. Starting from DNA gyrase inhibitor 1, we identified compound 27,…
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Keywords:
activity acinetobacter;
activity;
acinetobacter baumannii;
baumannii pseudomonas ... See more keywords
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Published in 2020 at "Microbial drug resistance"
DOI: 10.1089/mdr.2019.0214
Abstract: Acinetobacter baumannii and Pseudomonas aeruginosa are the most relevant Gram-negative bacteria associated with hospital and opportunistic infections. This study aimed to evaluate the dynamics of drug-resistant A. baumannii and P. aeruginosa and biofilm formers from…
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Keywords:
pseudomonas aeruginosa;
drug;
baumannii pseudomonas;
drug resistant ... See more keywords
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Published in 2020 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkaa117
Abstract: Abstract Background Cefiderocol is a novel siderophore cephalosporin, developed for activity against MDR Gram-negative bacilli (MDR-GNB). Objectives To assess the in vitro antibacterial activity of cefiderocol against a collection of MDR-GNB clinical isolates from hospitals…
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Keywords:
pseudomonas aeruginosa;
activity cefiderocol;
baumannii pseudomonas;
cefiderocol ... See more keywords