Expression of Bax and Bcl-2 Proteins in Left-Ventricular Cardiomyocytes in Wistar-Kyoto and SHR Rats with Insulin-Dependent Diabetes Mellitus.
Sign Up to like & getrecommendations! Published in 2021 at "Bulletin of experimental biology and medicine"
DOI: 10.1007/s10517-021-05272-7
Abstract: Loss of cardiomyocytes due to apoptotic or necrotic death is an important component of the pathogenesis of heart failure. Initiation of apoptosis by the mitochondrial pathway depends on the balance between proapoptotic and antiapoptotic factors,… read more here.
Keywords: bax; bax bcl; expression bax; diabetes mellitus ... See more keywords
To Study the Anti-cancer Effects of Shigella Flexneri in AspC-1 Pancreatic Cancer Cell Line in Approach to Bax and bcl-2 Genes
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Gastrointestinal Cancer"
DOI: 10.1007/s12029-020-00433-9
Abstract: Cancer is the uncontrolled division of cells and can be caused by genetic or environmental factors. Pancreatic cancer is one of the deadliest among all cancers. The role of bacteria as an anticancer agent dates… read more here.
Keywords: bax bcl; pancreatic cancer; bcl genes; cancer ... See more keywords
The novel Indole‐3‐formaldehyde (2‐AITFEI‐3‐F) is involved in processes of apoptosis induction?
Sign Up to like & getrecommendations! Published in 2017 at "Life Sciences"
DOI: 10.1016/j.lfs.2017.05.026
Abstract: Aim and objectives: Balancing between Bax and Bcl‐2 plays critical roles in both proliferation and self‐renewal activation of cancer cells. Indole‐3‐formaldehyde derivatives limit the growth and facilitate cell death in different cell systems. In this… read more here.
Keywords: novel indole; apoptosis; indole formaldehyde; aitfei ... See more keywords
Differential expression of Bax-Bcl-2 and PARP-1 confirms apoptosis of EAC cells in Swiss albino mice by Morus laevigata.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of food biochemistry"
DOI: 10.1111/jfbc.13342
Abstract: A safer natural alternative to treat neoplastic cells by inducing apoptosis is a prime requisite. Therefore, the current study was to evaluate the antiproliferative activity of Morus laevigata, a wild-type Mulberry species. Antioxidant and cytotoxic… read more here.
Keywords: parp; expression; bax bcl; apoptosis ... See more keywords
Interaction between Bax and Bcl-XL proteins confirmed by partial acceptor photobleaching-based FRET imaging
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Innovative Optical Health Sciences"
DOI: 10.1142/s179354582050011x
Abstract: Exact interaction mechanism between Bax and Bcl-XL, two key Bcl-2 family proteins, is an interesting and controversial issue. Partial acceptor photobleaching-based quantitative fluorescence resonan... read more here.
Keywords: partial acceptor; bax bcl; photobleaching based; acceptor photobleaching ... See more keywords
Apoptosis Resistance and NOTCH1 Mutations Impair Clinical Outcome in Chronic Lymphocytic Leukemia (CLL) Patients Treated with Ibrutinib
Sign Up to like & getrecommendations! Published in 2017 at "Blood"
DOI: 10.1182/blood.v130.suppl_1.261.261
Abstract: Ibrutinib, an oral, selective inhibitor of Bruton9s tyrosyne kinase (BTK), demonstrated superior overall response rate (ORR), progression-free survival (PFS) and overall survival (OS) compared with chemoimmunotherapy in CLL both in first line and in relapsed/refractory… read more here.
Keywords: pfs; patients treated; bax bcl; treated ibrutinib ... See more keywords
Bax, Bcl-2, and Bax/Bcl-2 as prognostic markers in acute myeloid leukemia: are we ready for Bcl-2-directed therapy?
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Management and Research"
DOI: 10.2147/cmar.s154608
Abstract: Purpose Many anticancer drugs induce apoptosis in malignant cells, and resistance to apoptosis could lead to suboptimal or no therapeutic benefit. Two cytoplasmic proteins, B-cell lymphoma protein 2 (Bcl-2)-associated X (Bax) and Bcl-2, act as… read more here.
Keywords: bax bcl; expression; acute myeloid; bcl ... See more keywords
Activation of apoptosis and G0/G1 cell cycle arrest along with inhibition of melanogenesis by humic acid and fulvic acid: BAX/BCL-2 and Tyr genes expression and evaluation of nanomechanical properties in A375 human melanoma cell line
Sign Up to like & getrecommendations! Published in 2022 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2022.60651.13444
Abstract: Objective(s): Humic acid (HA) and Fulvic acid (FA) are major members of humic substances, which are extracted from organic sources including soil and peat. The pro-apoptotic and anti-melanogenic effects of HA and FA at the… read more here.
Keywords: cell; bcl tyr; expression; acid ... See more keywords
Expressions and effects of G250, Bax and Bcl-2 in rats with renal clear cell carcinoma.
Sign Up to like & getrecommendations! Published in 2018 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201807_15502
Abstract: OBJECTIVE To investigate the expressions and effects of G250, B-cell lymphoma-2 associated X protein (Bax) and Bcl-2 in rats with renal clear cell carcinoma (RCCC). MATERIALS AND METHODS A total of 66 male Sprague-Dawley (SD)… read more here.
Keywords: bax bcl; cell carcinoma; cell; group ... See more keywords
Bax/Bcl-2 Cascade Is Regulated by the EGFR Pathway: Therapeutic Targeting of Non-Small Cell Lung Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.869672
Abstract: Non-small cell lung carcinoma (NSCLC) comprises 80%–85% of lung cancer cases. EGFR is involved in several cancer developments, including NSCLC. The EGFR pathway regulates the Bax/Bcl-2 cascade in NSCLC. Increasing understanding of the molecular mechanisms… read more here.
Keywords: lung; bax bcl; egfr pathway; lung cancer ... See more keywords
Hyperglycemia Promotes Chemoresistance Through the Reduction of the Mitochondrial DNA Damage, the Bax/Bcl-2 and Bax/Bcl-XL Ratio, and the Cells in Sub-G1 Phase Due to Antitumoral Drugs Induced-Cytotoxicity in Human Colon Adenocarcinoma Cells
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2018.00866
Abstract: Diabetes and cancer are common, chronic, and potentially fatal diseases that frequently co-exist. Observational studies clearly indicate that the risk of several types of cancer is increased in diabetic patients and a number of cancer… read more here.
Keywords: bax; colon adenocarcinoma; bax bcl; human colon ... See more keywords