Cimetidine a promising radio‐protective agent through modulating Bax/Bcl2 ratio: An in vivo study in male rats
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29692
Abstract: Radiotherapy is one of the most effective modalities for treatment of neoplastic diseases. Radiation damage is to a large extent caused by overproduction of reactive oxygen species. To improve the therapeutic index, identifying effective substances… read more here.
Keywords: bax; bax bcl2; bcl2 ratio; study ... See more keywords
Neuro‐Protective Effects of Resveratrol on Carbon Monoxide‐Induced Toxicity in Male Rats
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DOI: 10.1002/ptr.5855
Abstract: Acute carbon monoxide (CO) poisoning causes neurotoxicity through induction of necrosis, apoptosis, lipid peroxidation and oxidative stress. Resveratrol (RES) is a natural polyphenolic phytoalexin that exhibits neuroprotective effects in ischemia/reperfusion due to its anti‐apoptotic, anti‐necrotic… read more here.
Keywords: carbon; neuro protective; bax bcl2; lipid peroxidation ... See more keywords
5-Fluorouracil disrupts ovarian preantral follicles in young C57BL6J mice
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DOI: 10.1007/s00280-020-04217-7
Abstract: 5-Fluorouracil (5-FU), an anti-cancer drug, has been used for hepatoblastoma (HB) chemotherapy in children, who may have impaired ovarian follicle pool reserve with lasting effects to reproduction. Therefore, this study aimed to investigate 5-FU effects… read more here.
Keywords: preantral follicles; bax bcl2; fluorouracil; ovarian preantral ... See more keywords