Articles with "bay 6035" as a keyword



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Abstract 1646: Discovery and characterization of BAY-6035, a novel benzodiazepine-based SMYD3 inhibitor

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Published in 2018 at "Cancer Research"

DOI: 10.1158/1538-7445.am2018-1646

Abstract: SMYD3 (SET and MYND domain-containing protein 3) is a protein lysine methyltransferase (PKMT) which was initially described as H3K4 methyltransferase involved in transcriptional regulation. SMYD3 has recently been reported to methylate and regulate several non-histone… read more here.

Keywords: smyd3; inhibitor; bay 6035; benzodiazepine based ... See more keywords