Discovery of BAY-985 a highly selective TBK1/Ikkε inhibitor.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.9b01460
Abstract: . The serine/threonine kinase TBK1 (TANK-binding kinase 1) and its homologue IKKε are non-canonical members of the inhibitor of nuclear factor κB (IκB) kinase family. These kinases play important roles in multiple cellular pathways and,… read more here.
Keywords: highly selective; tbk1; bay 985; tbk1 ikk ... See more keywords