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Published in 2022 at "BMC Medical Research Methodology"
DOI: 10.1186/s12874-022-01513-z
Abstract: Background Adaptive clinical trials have been increasingly commonly employed to select a potential target population for one trial without conducting trials separately. Such enrichment designs typically consist of two or three stages, where the first…
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Keywords:
clinical trials;
binary outcome;
randomized clinical;
design randomized ... See more keywords
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Published in 2021 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph18020530
Abstract: This paper presents a brief overview of the recent literature on adaptive design of clinical trials from a Bayesian perspective for statistically not so sophisticated readers. Adaptive designs are attracting a keen interest in several…
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Keywords:
design adaptive;
adaptive clinical;
clinical trials;
bayesian design ... See more keywords