Enrichment Bayesian design for randomized clinical trials using categorical biomarkers and a binary outcome
Sign Up to like & getrecommendations! Published in 2022 at "BMC Medical Research Methodology"
DOI: 10.1186/s12874-022-01513-z
Abstract: Background Adaptive clinical trials have been increasingly commonly employed to select a potential target population for one trial without conducting trials separately. Such enrichment designs typically consist of two or three stages, where the first… read more here.
Keywords: clinical trials; binary outcome; randomized clinical; design randomized ... See more keywords
The Bayesian Design of Adaptive Clinical Trials
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DOI: 10.3390/ijerph18020530
Abstract: This paper presents a brief overview of the recent literature on adaptive design of clinical trials from a Bayesian perspective for statistically not so sophisticated readers. Adaptive designs are attracting a keen interest in several… read more here.
Keywords: design adaptive; adaptive clinical; clinical trials; bayesian design ... See more keywords