BayeStab: Predicting effects of mutations on protein stability with uncertainty quantification
Sign Up to like & getrecommendations! Published in 2022 at "Protein Science"
DOI: 10.1002/pro.4467
Abstract: Predicting protein thermostability change upon mutation is crucial for understanding diseases and designing therapeutics. However, accurately estimating Gibbs free energy change of the protein remained a challenge. Some methods struggle to generalize on examples with… read more here.
Keywords: bayestab predicting; uncertainty; predicting effects; bayestab ... See more keywords