Abstract LB324: BB3008, a potent and selective small molecular HPK1 inhibitor effective in multiple syngeneic tumor models
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DOI: 10.1158/1538-7445.am2023-lb324
Abstract: Introduction: Hematopoietic progenitor kinase 1 (HPK1) is a serine/threonine kinase in the MAP4K family predominantly expressed in immune cells, and has been identified as a negative regulator of T cell and B cell receptor signaling… read more here.
Keywords: hpk1 inhibitor; cell; tumor models; bb3008 ... See more keywords