The Cdkn2a gene product p19 alternative reading frame (p19ARF) is a critical regulator of IFNβ-mediated Lyme arthritis
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DOI: 10.1371/journal.ppat.1010365
Abstract: Type I interferon (IFN) has been identified in patients with Lyme disease, and its abundant expression in joint tissues of C3H mice precedes development of Lyme arthritis. Forward genetics using C3H mice with severe Lyme… read more here.
Keywords: arthritis; ifn; mice; cdkn2a gene ... See more keywords