Blood brain barrier leakage is not a consistent feature of white matter lesions in CADASIL
Sign Up to like & getrecommendations! Published in 2019 at "Acta Neuropathologica Communications"
DOI: 10.1186/s40478-019-0844-x
Abstract: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a genetic paradigm of small vessel disease (SVD) caused by NOTCH3 mutations that stereotypically lead to the vascular accumulation of NOTCH3 around smooth muscle… read more here.
Keywords: cadasil; bbb; bbb leakage; leakage ... See more keywords
Therapeutic Treatment with Pycnogenol® Attenuates Ischemic Brain Injury in Gerbils Focusing on Cognitive Impairment, Neuronal Death, BBB Leakage and Neuroinflammation in the Hippocampus.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of integrative neuroscience"
DOI: 10.31083/j.jin2202026
Abstract: BACKGROUND A gerbil model of ischemia and reperfusion (IR) injury in the forebrain has been developed for studies on mechanisms, prevention and therapeutic strategies of IR injury in the forebrain. Pycnogenol® (PYC), a standardized extract… read more here.
Keywords: brain; pycnogenol; bbb leakage; injury ... See more keywords