Branched chain amino acids, aging and age-related health
Sign Up to like & getrecommendations! Published in 2020 at "Ageing Research Reviews"
DOI: 10.1016/j.arr.2020.101198
Abstract: Branched chain amino acids (BCAA: leucine, valine, isoleucine) have key physiological roles in the regulation of protein synthesis, metabolism, food intake and aging. Many studies report apparently inconsistent conclusions about the relationships between blood levels… read more here.
Keywords: branched chain; bcaas; amino acids; age related ... See more keywords
BCAAs and Di-Alanine supplementation in the prevention of skeletal muscle atrophy: preclinical evaluation in a murine model of hind limb unloading.
Sign Up to like & getrecommendations! Published in 2021 at "Pharmacological research"
DOI: 10.1016/j.phrs.2021.105798
Abstract: Skeletal muscle atrophy occurs in response to various pathophysiological stimuli, including disuse, aging, and neuromuscular disorders, mainly due to an imbalance of anabolic/catabolic signaling. Branched Chain Amino Acids (BCAAs: leucine, isoleucine, valine) supplements can be… read more here.
Keywords: bcaas; muscle; murine model; atrophy ... See more keywords
Newly characterized mitochondrial BCAA transporter
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Endocrinology"
DOI: 10.1038/s41574-019-0262-y
Abstract: Emerging evidence suggests that brown adipose tissue (BAT) has roles outside of thermogenesis, including acting as a metabolic sink for glucose and fatty acids. Now, Shingo Kajimura and colleagues report that the catabolism of branched-chain… read more here.
Keywords: bcaas; bat; mitochondrial bcaa; bcaa ... See more keywords
Branched chain amino acids alter fatty acid profile in colostrum of sows fed a high fat diet
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Animal Science and Biotechnology"
DOI: 10.1186/s40104-019-0423-9
Abstract: Background Branched chain amino acids (BCAAs) are important substrates for milk protein synthesis in the mammary gland, and are tightly related to lipid metabolism. No study has been performed examining the role of BCAAs with… read more here.
Keywords: fat diet; bcaas; fatty acid; colostrum ... See more keywords
Branched-chain amino acids supplementation has beneficial effects on the progression of liver cirrhosis: A meta-analysis
Sign Up to like & getrecommendations! Published in 2022 at "World Journal of Clinical Cases"
DOI: 10.12998/wjcc.v10.i30.10984
Abstract: BACKGROUND Liver cirrhosis (LC) is currently the 11th most common cause of death and 15th cause of morbidity globally. The treatment of LC is mainly aimed at etiological intervention, lifestyle intervention, prevention and treatment of… read more here.
Keywords: amino acids; liver cirrhosis; branched chain; bcaas ... See more keywords
New Evidence of Oral Branched-Chain Amino Acid Supplementation on the Prognosis of Patients With Advanced Liver Disease
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Gastroenterology"
DOI: 10.14309/ctg.0000000000000542
Abstract: INTRODUCTION: Oral branched-chain amino acids (BCAAs) might benefit patients with advanced liver disease. We assess its effects on prognosis compared with control from the meta-analysis. METHODS: Study end points were development of hepatic encephalopathy (HE),… read more here.
Keywords: branched chain; patients advanced; bcaas; oral branched ... See more keywords
Dietary Branched-Chain Amino Acids (BCAAs) and Risk of Dyslipidemia in a Chinese Population
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14091824
Abstract: This study aimed to explore the association between dietary BCAAs, blood lipid levels and risk of dyslipidemia. In this case–control study, a total of 9541 subjects with normal blood lipids were included as a control… read more here.
Keywords: bcaas risk; risk dyslipidemia; dietary bcaas; bcaas ... See more keywords
Association of Circulating Branched-Chain Amino Acids with Cardiovascular Diseases: A Mendelian Randomization Study
Sign Up to like & getrecommendations! Published in 2023 at "Nutrients"
DOI: 10.3390/nu15071580
Abstract: Background: There have been reports linking branched-chain amino acids (BCAAs) to the hazard of various cardiovascular diseases (CVDs); however, the causal role of this relationship is still unclear. We conducted a study using bi-directional two-sample… read more here.
Keywords: branched chain; cardiovascular diseases; bcaas; association ... See more keywords
Reduction of Plasma BCAAs following Roux-en-Y Gastric Bypass Surgery Is Primarily Mediated by FGF21
Sign Up to like & getrecommendations! Published in 2023 at "Nutrients"
DOI: 10.3390/nu15071713
Abstract: Type 2 diabetes (T2D) is a challenging health concern worldwide. A lifestyle intervention to treat T2D is difficult to adhere, and the effectiveness of approved medications such as metformin, thiazolidinediones (TZDs), and sulfonylureas are suboptimal.… read more here.
Keywords: surgery; bcaas; plasma bcaas; reduction ... See more keywords