BCAS2, a protein enriched in advanced prostate cancer, interacts with NBS1 to enhance DNA double-strand break repair
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Cancer"
DOI: 10.1038/s41416-020-01086-y
Abstract: Background Breast cancer amplified sequence 2 (BCAS2) plays crucial roles in pre-mRNA splicing and androgen receptor transcription. Previous studies suggested that BCAS2 is involved in double-strand breaks (DSB); therefore, we aimed to characterise its mechanism… read more here.
Keywords: bcas2; interacts nbs1; prostate cancer; double strand ... See more keywords
BCAS2 promotes primitive hematopoiesis by sequestering β-catenin within the nucleus
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DOI: 10.1101/2024.07.17.603892
Abstract: Breast carcinoma amplified sequence 2 (BCAS2), a core component of the hPrP19 complex, plays crucial roles in various physiological and pathological processes. However, whether BCAS2 has functions other than being a key RNA-splicing regulator within… read more here.
Keywords: within nucleus; sequestering catenin; bcas2; primitive hematopoiesis ... See more keywords
Circular RNA NEK6 contributes to the development of non-small-cell lung cancer by competitively binding with miR-382-5p to elevate BCAS2 expression at post-transcriptional level
Sign Up to like & getrecommendations! Published in 2021 at "BMC Pulmonary Medicine"
DOI: 10.1186/s12890-021-01617-0
Abstract: Background Non-small-cell lung cancer (NSCLC) is the commonest type of lung cancer, which is one of most deadly cancers that possess high morbidity and mortality all over the world. The function of circular RNA NIMA… read more here.
Keywords: bcas2; mir 382; circ nek6; expression ... See more keywords