Examining Uncertainty in in Vitro-in Vivo Extrapolation Applied in Fish Bioconcentration Models.
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DOI: 10.1021/acs.est.0c01492
Abstract: In vitro biotransformation rates were determined for 30 chemicals, mostly fragrance ingredients, using trout liver S9 fractions (RT-S9) and incorporated into in vitro-in vivo extrapolation (IVIVE) models to predict bioconcentration factors (BCFs). Predicted BCFs were… read more here.
Keywords: bcfs; bioconcentration; vitro vivo; biotransformation ... See more keywords