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Published in 2020 at "Journal of Urology"
DOI: 10.1097/ju.0000000000000823.02
Abstract: INTRODUCTION AND OBJECTIVE:Alternatives to radical cystectomy (RC) are critically needed for the treatment of high-risk BCG-unresponsive NMIBC. Vicinium is a recombinant fusion protein comprised of...
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Keywords:
phase results;
bcg unresponsive;
results vicinium;
vicinium bcg ... See more keywords
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Published in 2020 at "Journal of Urology"
DOI: 10.1097/ju.0000000000000846.01
Abstract: INTRODUCTION AND OBJECTIVE:There is an unmet clinical need for new drugs able to delay or avoid cystectomy in patients with CIS unresponsive to BCG. Oncofid - P-B, a new drug that originates from t...
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Keywords:
pd12 oncofid;
bcg unresponsive;
unresponsive carcinoma;
treatment bcg ... See more keywords
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Published in 2020 at "Journal of Urology"
DOI: 10.1097/ju.0000000000001515
Abstract: PURPOSE Patients with BCG-unresponsive carcinoma in situ (CIS) are treated with radical cystectomy (RCx) or salvage intravesical chemotherapy (SIC). Recently, pembrolizumab was approved for BCG-unresponsive CIS. MATERIALS AND METHODS We used a decision-analytic Markov model…
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Keywords:
bcg unresponsive;
pembrolizumab;
cost effective;
rcx ... See more keywords
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Published in 2020 at "Current Opinion in Urology"
DOI: 10.1097/mou.0000000000000846
Abstract: PURPOSE OF REVIEW A number of promising therapies for Bacillus Calmette-Guerin (BCG) unresponsive nonmuscle invasive bladder cancer (NMIBC) are in the pipeline. In this review, we discuss the history of immunotherapy for the treatment of…
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Keywords:
bcg unresponsive;
cancer;
calmette guerin;
guerin bcg ... See more keywords
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Published in 2021 at "BJU international"
DOI: 10.1111/bju.15567
Abstract: OBJECTIVE To assess whether bacillus Calmette-Guérin (BCG) responsiveness after initiation of an adequate BCG treatment (at least five of six instillations of induction and at least two of three instillations of maintenance) impacts oncological outcomes…
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Keywords:
bcg immunotherapy;
adequate bcg;
bcg unresponsive;
months iqr ... See more keywords
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Published in 2022 at "BMC Urology"
DOI: 10.1186/s12894-022-00959-z
Abstract: Background Intravesical bacillus Calmette-Guérin (BCG) fails in a considerable proportion of non-muscle invasive bladder cancer (NMIBC) patients despite treatment per recommended protocol. This real-world study aimed to understand the current patterns of treatment and disease…
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Keywords:
bcg unresponsive;
treatment;
bladder;
bcg ... See more keywords