Association of BCG Vaccine Treatment With Death and Dementia in Patients With Non–Muscle-Invasive Bladder Cancer
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.14336
Abstract: Key Points Question Does the BCG vaccine have a protective association with the risk of Alzheimer disease and related dementias (ADRD)? Findings In this cohort study of 6467 patients with non–muscle-invasive bladder cancer, treatment with… read more here.
Keywords: bladder cancer; treatment; bcg vaccine;
Is BCG associated with reduced incidence of COVID-19? A meta-regression of global data from 160 countries
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Epidemiology and Global Health"
DOI: 10.1016/j.cegh.2020.08.015
Abstract: Background Global research is running towards to find a vaccine to stop the threat of the COVID-19. The Bacillus Calmette–Guérin (BCG) vaccine that prevents severe forms of tuberculosis is getting more attention in this scenario.… read more here.
Keywords: data 160; bcg vaccine; coverage; incidence covid ... See more keywords
SapM mutation to improve the BCG vaccine: Genomic, transcriptomic and preclinical safety characterization.
Sign Up to like & getrecommendations! Published in 2019 at "Vaccine"
DOI: 10.1016/j.vaccine.2019.05.022
Abstract: The Mycobacterium bovis Bacille Calmette Guérin (BCG) vaccine shows variable efficacy in protection against adult tuberculosis (TB). Earlier, we have described a BCG mutant vaccine with a transposon insertion in the gene coding for the… read more here.
Keywords: bcg; bcg vaccine; sapm; live attenuated ... See more keywords
Efficacy of BCG vaccine in animal models of neurological disorders.
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DOI: 10.1016/j.vaccine.2021.12.005
Abstract: The Bacillus Calmette-Guerin (BCG) vaccine can modulate the immune response via antigen-specific immune response, but also it can confer nonspecific protection and therapeutic benefits in several neurological conditions through different heterologous effects of vaccination. However,… read more here.
Keywords: vaccine animal; animal models; bcg; efficacy bcg ... See more keywords
COVID-19 pandemic: SARS-CoV-2 specific vaccines and challenges, protection via BCG trained immunity, and clinical trials
Sign Up to like & getrecommendations! Published in 2021 at "Expert Review of Vaccines"
DOI: 10.1080/14760584.2021.1938550
Abstract: ABSTRACT Introduction: The coronavirus disease 2019 (COVID-19) pandemic continues to spread worldwide and vaccination remains the most effective approach to control COVID-19. Currently, at least ten COVID-19 vaccines have been authorized under emergency authorization. However,… read more here.
Keywords: bcg vaccine; covid pandemic; covid vaccines; clinical trials ... See more keywords
Randomized clinical trial of BCG vaccine in patients with convalescent COVID‐19: Clinical evolution, adverse events, and humoral immune response
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DOI: 10.1111/joim.13523
Abstract: The Bacillus Calmette–Guérin (BCG) vaccine may confer cross‐protection against viral diseases in adults. This study evaluated BCG vaccine cross‐protection in adults with convalescent coronavirus disease 2019 (COVID‐19). read more here.
Keywords: randomized clinical; bcg vaccine; bcg; clinical trial ... See more keywords
Curcumin Nanoparticles Enhance Mycobacterium bovis BCG Vaccine Efficacy by Modulating Host Immune Responses
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DOI: 10.1128/iai.00291-19
Abstract: Tuberculosis (TB) is one of the deadliest diseases, causing ∼2 million deaths annually worldwide. Mycobacterium bovis bacillus Calmette-Guérin (BCG), the only TB vaccine in common use, is effective against disseminated and meningeal TB in young… read more here.
Keywords: mycobacterium bovis; curcumin nanoparticles; efficacy; bcg ... See more keywords
A lipidated peptide of Mycobacterium tuberculosis resuscitates the protective efficacy of BCG vaccine by evoking memory T cell immunity
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Translational Medicine"
DOI: 10.1186/s12967-017-1301-x
Abstract: BackgroundThe current BCG vaccine induces only short-term protection against Mycobacterium tuberculosis (Mtb), suggesting its failure to generate long-lasting memory T cells. Previously, we have demonstrated that a self-adjuvanting peptide of Mtb (L91), successfully generated enduring… read more here.
Keywords: bcg; l91; bcg vaccine; memory ... See more keywords
Is the BCG Vaccine an Answer to Future Pandemic Preparedness?
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DOI: 10.3390/vaccines10020201
Abstract: While the development of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines was rapid, time to development and implementation challenges remain that may impact the response to future pandemics. Trained immunity via bacille Calmette-Guerin (BCG)… read more here.
Keywords: future pandemic; pandemic preparedness; answer future; vaccine answer ... See more keywords
Report of 16 Years of the BCG Vaccine under the Expanded Program on Immunizations in Mexico (2006–2021)
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DOI: 10.3390/vaccines11020337
Abstract: Background: In recent years in Mexico, a decreased Bacillus Calmette and Guérin (BCG) coverage has been observed concomitantly with new cases of tuberculosis. Material and Methods: This study is a descriptive and analytical evaluation regarding… read more here.
Keywords: report years; last years; coverage; 2006 2021 ... See more keywords
In vitro and in vivo assessments for developing an oral BCG vaccine formulation
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DOI: 10.38212/2224-6614.2404
Abstract: The aim of this study was to establish in vitro analytical methods for assessing an investigated oral BCG vaccine formulation. In addition, in vivo immune response was also evaluated in guinea pigs by determining the… read more here.
Keywords: vaccine formulation; oral bcg; bcg vaccine; formulation ... See more keywords