ΔN-Bcl-xL, a therapeutic target for neuroprotection
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DOI: 10.4103/1673-5374.219033
Abstract: The B-cell lymphoma-extra large (Bcl-xL) is a mitochondrial anti-apoptotic protein that plays a role in neuroprotection. However, during excitotoxic stimulation, Bcl-xL undergoes caspase-dependent cleavage and produces a fragmented form, ΔN-Bcl-xL. Accumulation of ΔN-Bcl-xL is associated… read more here.
Keywords: bcl therapeutic; abt 737; bcl; neuroprotection ... See more keywords