Prospective Validation of Diagnostic Tumor Biomarkers in Men Treated With Radiotherapy for Prostate Cancer
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the National Cancer Institute"
DOI: 10.1093/jnci/djw232
Abstract: Background: In prior retrospective studies, we assessed a number of prostate tumor tissue biomarkers that were associated independently with the clinical outcome of men treated with radiotherapy (RT) ± androgen deprivation therapy (ADT). In this… read more here.
Keywords: men treated; prostate cancer; treated radiotherapy; bcl2 bax ... See more keywords
Transcriptome analysis of ABCB1, ABCG2 and the BCL2/BAX ratio in refractory and relapsed canine lymphomas under treatment and rescue protocol
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DOI: 10.2478/acve-2018-0002
Abstract: Abstract The main problems that cause unresponsiveness to an anti-neoplastic drug are the overexpression of drug resistant and anti-apoptotic proteins in tumor cells. In a rescue protocol we evaluated the ability of toceranib phosphate concurrent… read more here.
Keywords: abcg2 bcl2; treatment; rescue; bcl2 bax ... See more keywords
The influence of BCL2, BAX, and ABCB1 gene expression on prognosis of adult de novo acute myeloid leukemia with normal karyotype patients
Sign Up to like & getrecommendations! Published in 2023 at "Radiology and Oncology"
DOI: 10.2478/raon-2023-0017
Abstract: Abstract Background Deregulation of the apoptotic process underlies the pathogenesis of many cancers, including leukemia, but is also very important for the success of chemotherapy treatment. Therefore, the gene expression profile of main apoptotic factors,… read more here.
Keywords: bcl2; bcl2 bax; expression; gene expression ... See more keywords
Bexarotene enhances heart structure and function in diabetic rats by inhibiting ventricular remodeling and cardiomyocyte apoptosis
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DOI: 10.4314/tjpr.v18i7.14
Abstract: Purpose: To investigate the influence of bexarotene (Bex) on cardiac structure and function in streptozotocin (STZ)-induced diabetes mellitus (DM) rats, and the mechanism of action involved. Methods: Four groups of Sprague Dawley rats (n =… read more here.
Keywords: structure function; bexarotene; structure; bcl2 bax ... See more keywords