INNV-02. Central nervous system tumor with BCOR/BCORL1 fusion: a rare and novel CNS tumor entity treated with radiation and temozolomide
Sign Up to like & getrecommendations! Published in 2025 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaf201.0891
Abstract: The Central Nervous System (CNS) tumor with BCL6 Corepressor (BCOR) tumors are newly identified tumor entities as of the 2021 World (WHO) Classification of CNS Tumors. With less than 50 cases reported in literature to… read more here.
Keywords: tumor; bcor bcorl1; cns tumor;
Characteristics and clinical outcomes of ND-AML patients with bcor/bcorl1 mutations
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DOI: 10.1182/blood-2025-7005
Abstract: 1.Background: Acute myeloid leukemia (AML) remains a challenging hematologic malignancy with heterogeneous genetic and clinical features. BCOR and BCORL1 mutations, occurring in approximately 3-5%[1] of AML cases, have been classified as adverse prognostic markers together… read more here.
Keywords: reached ccr; cohort; bcor bcorl1; treatment ... See more keywords
BCOR, BCORL1, and BCL6 Mutations in Pediatric Leukemias
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DOI: 10.3390/cancers17152443
Abstract: Simple Summary Genetic changes play an important role in the development of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). Some rare genetic mutations, specifically in the BCOR and BCORL1 genes, have been found in… read more here.
Keywords: mutations pediatric; bcor bcorl1; bcorl1 bcl6; bcl6 mutations ... See more keywords