Usefulness of BCOR gene mutation as a prognostic factor in acute myeloid leukemia with intermediate cytogenetic prognosis
Sign Up to like & getrecommendations! Published in 2018 at "Genes"
DOI: 10.1002/gcc.22542
Abstract: BCOR gene is a transcription regulatory factor that plays an essential role in normal hematopoiesis. The wider introduction of next‐generation sequencing technology has led to reports in recent years of mutations in the BCOR gene… read more here.
Keywords: intermediate cytogenetic; bcor gene; prognosis; factor ... See more keywords
Cushing's syndrome secondary to typical pulmonary carcinoid with mutation in BCOR gene
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DOI: 10.1097/md.0000000000007870
Abstract: Rationale: Typical pulmonary carcinoid is a kind of low-grade malignancy neuroendocrine tumor. Cushing's syndrome is a very rare clinical feature of typical pulmonary carcinoid caused by hypercorticism. Complete tumor resection is the standard curative treatment… read more here.
Keywords: cushing syndrome; bcor gene; pulmonary carcinoid; typical pulmonary ... See more keywords
Clear cell sarcomas of the kidney are characterised by BCOR gene abnormalities, including exon 15 internal tandem duplications and BCOR–CCNB3 gene fusion
Sign Up to like & getrecommendations! Published in 2018 at "Histopathology"
DOI: 10.1111/his.13366
Abstract: Clear cell sarcoma of the kidney (CCSK) is a rare paediatric renal malignant tumour. The majority of CCSKs have internal tandem duplications (ITDs) of the BCOR gene, whereas a minority have the YWHAE–NUTM2 gene fusion.… read more here.
Keywords: bcor gene; internal tandem; clear cell; fusion ... See more keywords
BCOR gene alterations in hematological diseases.
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DOI: 10.1182/blood.2021010958
Abstract: The BCL6 co-repressor (BCOR) is a transcription factor involved in the control of embryogenesis, mesenchymal stem cells function, hematopoiesis and lymphoid development. Recurrent somatic clonal mutations of the BCOR gene and its homologue BCORL1 have… read more here.
Keywords: bcor gene; gene alterations; bcor; alterations hematological ... See more keywords