BCPP compounds, PET probes for early therapeutic evaluations, specifically bind to mitochondrial complex I.
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DOI: 10.1016/j.mito.2018.03.001
Abstract: BCPP compounds have been developed as PET imaging probes for neurodegenerative diseases in the living brain. 18F-BCPP-EF identifies damaged neuronal areas based on the lack of MC-I; however, its underlying mechanisms of action and specificity… read more here.
Keywords: probes early; early therapeutic; bcpp compounds; pet probes ... See more keywords