The inhibitory coreceptor CD22 restores B cell signaling by developmentally regulating Cd45−/− immunodeficient B cells
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DOI: 10.1126/scisignal.abf9570
Abstract: The protein tyrosine phosphatase CD45 plays a crucial role in B cell antigen receptor (BCR) signaling by activating Src family kinases. Cd45−/− mice show altered B cell development and a phenotype likely due to reduced… read more here.
Keywords: cd22; cell; bcr ligation; cd45 cells ... See more keywords