Humanized Candida and NanoBiT Assays Expedite Discovery of Bdf1 Bromodomain Inhibitors With Antifungal Potential
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DOI: 10.1002/advs.202404260
Abstract: The fungal Bromodomain and Extra‐Terminal (BET) protein Bdf1 is a potential antifungal target against invasive fungal infections. However, the need to selectively inhibit both Bdf1 bromodomains (BDs) over human orthologs and the lack of molecular… read more here.
Keywords: bdf1; inhibitors antifungal; bromodomain; candida ... See more keywords