Curcumin prevents cognitive deficits in the bile duct ligated rats
Sign Up to like & getrecommendations! Published in 2020 at "Psychopharmacology"
DOI: 10.1007/s00213-020-05633-6
Abstract: Bile duct ligation (BDL) in rodents can cause impaired liver function and cognition deficits. Curcumin has shown a preventive and therapeutic role in memory impairment. Therefore, this study aimed to explore the effect of curcumin… read more here.
Keywords: function; bdl rats; bile duct; rats curcumin ... See more keywords
Occurrence of pesticides residues in French beans, tomatoes, and kale in Kenya, and their human health risk indicators
Sign Up to like & getrecommendations! Published in 2020 at "Environmental Monitoring and Assessment"
DOI: 10.1007/s10661-020-08662-y
Abstract: Residue levels of seven commonly used pesticides were determined in random samples of tomatoes, French beans, and kale collected from horticultural farms in Buuri, Imenti North, and Imenti South sub-counties in Meru, Kenya, just before… read more here.
Keywords: human health; health risk; health; bdl ... See more keywords
Rosiglitazone ameliorates bile duct ligation-induced liver fibrosis by down-regulating NF-κB-TNF-α signaling pathway in a PPARγ-dependent manner.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.09.084
Abstract: Liver fibrosis is a major cause of morbidity and mortality worldwide. One of its therapeutic targets is peroxisome proliferator-activated receptor γ (PPARγ), with its ligands including rosiglitazone being tested in pre-clinical and clinical studies. However,… read more here.
Keywords: ppar; fibrosis; liver fibrosis; ppar dependent ... See more keywords
Skeletal Muscle Fibre Type Changes in an Avian Model of Hepatic Fibrosis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of comparative pathology"
DOI: 10.1016/j.jcpa.2021.01.001
Abstract: We investigated the susceptibility of type I and type II skeletal myofibres to atrophy in hens with hepatic fibrosis induced by bile duct ligation (BDL). Seven hens, approximately 2 years old, were randomly assigned to… read more here.
Keywords: bdl group; type fibres; hepatic fibrosis; type ... See more keywords
Targeting Keap‐1/Nrf‐2 pathway and cytoglobin as a potential protective mechanism of diosmin and pentoxifylline against cholestatic liver cirrhosis
Sign Up to like & getrecommendations! Published in 2018 at "Life Sciences"
DOI: 10.1016/j.lfs.2018.05.048
Abstract: Aim: The effects of diosmin (DS), pentoxifylline (PTX) and their combination on inflammatory response, oxidant/antioxidant balance, cytoglobin and cirrhotic reaction during bile duct ligation (BDL) were investigated and explored. Main methods: Fifty adult male Wistar… read more here.
Keywords: diosmin pentoxifylline; keap nrf; ptx; liver cirrhosis ... See more keywords
Protective Effects of Spermidine Against Cirrhotic Cardiomyopathy in Bile Duct-Ligated Rats.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000000872
Abstract: Cirrhotic cardiomyopathy is a critical factor that causes morbidity and mortality in crucial conditions such as liver transplantation. In animal model, the common pathophysiologic mechanisms of cirrhotic cardiomyopathy are similar to those associated with bile… read more here.
Keywords: cirrhotic cardiomyopathy; bile duct; bdl; effects spermidine ... See more keywords
Bayesian Deep Learning for Hyperspectral Image Classification With Low Uncertainty
Sign Up to like & getrecommendations! Published in 2023 at "IEEE Transactions on Geoscience and Remote Sensing"
DOI: 10.1109/tgrs.2023.3257865
Abstract: In recent years, deep learning models have been widely used for hyperspectral image (HSI) classification, and most of the existing deep-learning-based methods merely focused on high classification accuracy. However, in real applications, classification with low… read more here.
Keywords: classification; uncertainty; deep learning; bdl ... See more keywords
Sex is associated with differences in oxidative stress and susceptibility to severe hepatic encephalopathy in bile‐duct ligated rats
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neurochemistry"
DOI: 10.1111/jnc.15661
Abstract: Hepatic encephalopathy (HE) is a debilitating neurological complication of chronic liver disease (CLD). Hyperammonemia plays an important role in HE's pathogenesis, acting synergistically with systemic oxidative stress. During CLD, muscle plays a compensatory role in… read more here.
Keywords: male bdl; bdl rats; oxidative stress; cld ... See more keywords
Bacterial DNA load in Staphylococcus aureus bacteremia is significantly higher in intravascular infections
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0266869
Abstract: Objectives Determination of pathogen-specific bacterial DNA load (BDL) in blood has been shown to be directly correlated with severity of infection in patients with bacteremia. In the diagnostic work-up of patients with Staphylococcus aureus bacteremia… read more here.
Keywords: dna load; intravascular infections; staphylococcus aureus; bacterial dna ... See more keywords
The Role of Gut Microbiota in Mice With Bile Duct Ligation-Evoked Cholestatic Liver Disease-Related Cognitive Dysfunction
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.909461
Abstract: The pathogenesis of Hepatic Encephalopathy (HE) is complex and multifactorial. The development of metagenomics sequencing technology led to show the significant role of gut microbiota in the pathogenesis of cognitive dysfunction, which paved the way… read more here.
Keywords: gut microbiota; cognitive dysfunction; role; dysfunction ... See more keywords
Triptolide increases resistance to bile duct ligation-induced liver injury and fibrosis in mice by inhibiting RELB
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.1032722
Abstract: Cholestasis is a common, chronic liver disease that may cause fibrosis and cirrhosis. Tripterygium wilfordii Hook.f (TWHF) is a species in the Euonymus family that is commonly used as a source of medicine and food… read more here.
Keywords: duct ligation; bdl induced; liver injury; bile duct ... See more keywords