The role of BDNF methylation and Val66Met in amygdala reactivity during emotion processing
Sign Up to like & getrecommendations! Published in 2019 at "Human Brain Mapping"
DOI: 10.1002/hbm.24825
Abstract: Epigenetic alterations of the brain‐derived neurotrophic factor (BDNF) gene have been associated with psychiatric disorders in humans and with differences in amygdala BDNF mRNA levels in rodents. This human study aimed to investigate the relationship… read more here.
Keywords: methylation; amygdala reactivity; bdnf methylation; bdnf ... See more keywords
Oxytocin receptor genes moderate BDNF epigenetic methylation by childhood trauma.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2022.03.020
Abstract: OBJECTIVES Gene-Environment (G × E) interaction is of increasing importance in understanding the pathophysiology of posttraumatic stress disorder (PTSD). This study investigated the interaction effect of childhood traumatic experience and epigenetic methylation of brain-derived neurotrophic factor (BDNF)… read more here.
Keywords: childhood trauma; effect; methylation; bdnf methylation ... See more keywords
Increased BDNF methylation in saliva, but not blood, of patients with borderline personality disorder
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Epigenetics"
DOI: 10.1186/s13148-018-0544-6
Abstract: BackgroundThe importance of epigenetic alterations in psychiatric disorders is increasingly acknowledged and the use of DNA methylation patterns as markers of disease is a topic of ongoing investigation. Recent studies suggest that patients suffering from… read more here.
Keywords: methylation; bpd; saliva blood; bdnf methylation ... See more keywords
Changes of BDNF exon IV DNA methylation are associated with methamphetamine dependence.
Sign Up to like & getrecommendations! Published in 2021 at "Epigenomics"
DOI: 10.2217/epi-2020-0463
Abstract: Aim: We investigated DNA methylation of BDNF in methamphetamine (METH) dependence in humans and an animal model. Materials & methods: BDNF methylation at exon IV was determined by pyrosequencing of blood DNA from METH-dependent and control… read more here.
Keywords: methylation; dependence; meth; dna methylation ... See more keywords
Multidimensional Analysis of Major Depression: Association Between BDNF Methylation, Psychosocial and Cognitive Domains
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2021.768680
Abstract: Major Depression is a complex disorder with a growing incidence worldwide and multiple variables have been associated with its etiology. Nonetheless, its diagnosis is continually changing and the need to understand it from a multidimensional… read more here.
Keywords: analysis; methylation; major depression; depression ... See more keywords
Modifying Effect of the Interleukin-18 Level on the Association between BDNF Methylation and Long-Term Cardiovascular Outcomes in Patients with Acute Coronary Syndrome
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DOI: 10.3390/ijms232315270
Abstract: This study investigated the potential modifying effects of the level of the serum interleukin-18 (IL-18) on the association between BDNF methylation status and long-term cardiovascular outcomes in patients with acute coronary syndrome (ACS). Hospitalized ACS… read more here.
Keywords: long term; methylation; association bdnf; level ... See more keywords