BDNFâoverexpressing human mesenchymal stem cells mediate increased neuronal protection in vitro
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DOI: 10.1002/jnr.24488
Abstract: The use of neurotrophic factors as therapeutic agents for neurodegenerative diseases is considered as an approach aimed at restoring and maintaining neuronal function in the peripheral and central nervous system. Since the neuroprotective effect is… read more here.
Keywords: human mesenchymal; bdnf overexpressing; delivery; bdnf ... See more keywords
Improvement of Cerebral Ischemia-Reperfusion Injury via Regulation of Apoptosis by Exosomes Derived from BDNF-Overexpressing HEK293
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DOI: 10.1155/2021/6613510
Abstract: Brain-derived neurotrophic factor (BDNF) provides neuroprotective effects towards therapeutic cerebral ischemia-reperfusion (I/R) injury. This view has been proposed by more and more evidence. However, due to the lack of permeability of the blood-brain barrier (BBB)… read more here.
Keywords: overexpressing hek293; apoptosis; bdnf overexpressing; cerebral ischemia ... See more keywords