Global epigenetic analysis of BDNF Val66Met mice hippocampus reveals changes in dendrite and spine remodeling genes
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DOI: 10.1002/hipo.22991
Abstract: Brain‐derived neurotrophic factor (BDNF), a neurotrophin highly expressed in the hippocampus, plays crucial roles in cognition, neuroplasticity, synaptic function, and dendritic remodeling. The common human Val66Met polymorphism of BDNF has been implicated in the pathophysiology… read more here.
Keywords: analysis; bdnf val66met; mice; dendrite spine ... See more keywords
Cerebellar transcranial direct current stimulation interacts with BDNF Val66Met in motor learning
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DOI: 10.1016/j.brs.2018.04.009
Abstract: BACKGROUND Cerebellar transcranial direct current stimulation has been reported to enhance motor associative learning and motor adaptation, holding promise for clinical application in patients with movement disorders. However, behavioral benefits from cerebellar tDCS have been… read more here.
Keywords: eyeblink conditioning; tdcs; motor; bdnf val66met ... See more keywords
The Correlation between Plasma Brain-derived Neurotrophic Factor and Cognitive Function in Bipolar Disorder is Modulated by the BDNF Val66Met Polymorphism
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DOI: 10.1016/j.eurpsy.2017.01.243
Abstract: Objectives Brain-derived neurotrophic factor (BDNF) may be involved in the pathogenesis of bipolar disorder (BD). The functional BDNF Val66Met polymorphism (rs6265) is associated with secretion of BDNF. The current study aimed to explore the correlation… read more here.
Keywords: plasma bdnf; correlation; bdnf val66met; val66met polymorphism ... See more keywords
Interaction between job stress and the BDNF Val66Met polymorphism affects depressive symptoms in Chinese healthcare workers.
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DOI: 10.1016/j.jad.2018.04.089
Abstract: BACKGROUND Chronic exposure to job-related stress can lead to depression and BDNF polymorphism may play an important role in this process. The role of the stress × BDNF Val66Met interaction in depression has been studied widely using… read more here.
Keywords: depressive symptoms; stress; job; bdnf val66met ... See more keywords
Genetics of stroke recovery: BDNF val66met polymorphism in stroke recovery and its interaction with aging
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DOI: 10.1016/j.nbd.2018.08.009
Abstract: Stroke leads to long term sensory, motor and cognitive impairments. Most patients experience some degree of spontaneous recovery which is mostly incomplete and varying greatly among individuals. The variation in recovery outcomes has been attributed… read more here.
Keywords: recovery; stroke recovery; genetics; bdnf val66met ... See more keywords
Variations in the APOE allele or BDNF Val66Met polymorphism are not associated with changes in cognitive function following a tertiary education intervention in older adults: the Tasmanian Healthy Brain Project
Sign Up to like & getrecommendations! Published in 2017 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2017.03.028
Abstract: The apolipoprotein (APOE) ε4 allele and the Met variant of the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism are associated with reduced cognitive function in older adults. The aim of this study was to examine the… read more here.
Keywords: function; apoe allele; bdnf val66met; cognitive function ... See more keywords
BDNF Val66Met polymorphism and posttraumatic stress symptoms in U.S. military veterans: Protective effect of physical exercise
Sign Up to like & getrecommendations! Published in 2019 at "Psychoneuroendocrinology"
DOI: 10.1016/j.psyneuen.2018.10.011
Abstract: The Met allele of the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is associated with reduced levels of BDNF release, heightened hypothalamic-pituitary-adrenal axis reactivity, and impaired fear extinction. As a result, Met allele carriers may be… read more here.
Keywords: ptsd symptoms; bdnf val66met; allele carriers; met allele ... See more keywords
Suicide Attempt, Clinical Correlates, and BDNF Val66Met Polymorphism in Chronic Patients With Schizophrenia
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DOI: 10.1037/neu0000383
Abstract: Objective: Recent evidence suggests the role of brain-derived neurotrophic factor (BDNF) in the pathophysiology of suicidal behavior. Because schizophrenia patients usually have high suicide rates and numerous studies have suggested that BDNF may contribute to… read more here.
Keywords: suicide attempts; patients schizophrenia; bdnf val66met; schizophrenia patients ... See more keywords
BDNF Val66Met polymorphism moderates the link between child maltreatment and reappraisal ability
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DOI: 10.1111/gbb.12366
Abstract: Child maltreatment is associated with increased risk for virtually all common mental disorders, but it is not yet clear why. One possible mechanism is emotion regulation ability. The present study investigated for the first time… read more here.
Keywords: ability; child maltreatment; reappraisal ability; bdnf val66met ... See more keywords
The BDNF Val66Met polymorphism impacts victim's moral emotions following interpersonal transgression.
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DOI: 10.1111/sjop.12678
Abstract: Immoral behaviors make individuals abominate and punish transgressors. Inspired by the associations between the Val66Met polymorphism of brain-derived neurotropic factor (BDNF) gene and emotional responses following negative events, we investigated whether this polymorphism was also… read more here.
Keywords: moral emotions; following interpersonal; bdnf val66met; val66met polymorphism ... See more keywords
Plasma BDNF Level in Major Depression: Biomarker of the Val66Met BDNF Polymorphism and of the Clinical Course in Met Carrier Patients
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DOI: 10.1159/000478862
Abstract: Aims: Despite the involvement of the brain-derived neurotrophic factor (BDNF) in the physiopathology of major depressive disorder (MDD), the coherence between the components of the BDNF pathway and their link with the clinical features of… read more here.
Keywords: plasma bdnf; bdnf val66met; val66met polymorphism; bdnf levels ... See more keywords