Molecular beacons with oxidized bases report on substrate specificity of DNA oxoguanine glycosylases
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DOI: 10.1039/d1sc05648d
Abstract: DNA glycosylase enzymes recognize and remove structurally distinct modified forms of DNA bases, thereby repairing genomic DNA from chemically induced damage or erasing epigenetic marks. However, these enzymes are often promiscuous, and advanced tools are… read more here.
Keywords: dna; molecular beacons; beacons oxidized; specificity ... See more keywords