A homogeneous magnetic bead-based impedance immunosensor for highly sensitive detection of Escherichia coli O157:H7
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical Engineering Journal"
DOI: 10.1016/j.bej.2020.107513
Abstract: Abstract As foodborne pathogen contamination has become a threat to human health worldwide, early detection of pathogen is significant. Traditional electrochemical immunosensors for pathogen detection involve electrode modification or samples adsorption on the electrode which… read more here.
Keywords: bead based; detection; magnetic bead; coli o157 ... See more keywords
The genesis and evolution of bead-based multiplexing.
Sign Up to like & getrecommendations! Published in 2019 at "Methods"
DOI: 10.1016/j.ymeth.2019.01.007
Abstract: Multiplexed analysis has the advantage of allowing for simultaneous detection of multiple analytes in a single reaction vessel which reduces time, labor, and cost as compared to single-reaction-based detection methods. Microsphere-based suspension array technologies, such… read more here.
Keywords: bead based; genesis evolution; detection; medicine ... See more keywords
Digital Protein Detection in Bulk Solutions
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c04666
Abstract: Quick and accurate molecular diagnostics in protein detection can greatly benefit medicine in disease diagnosis and lead to positive patient outcomes. However, specialized equipment used in clinical laboratories often comes with trade-offs between operation and… read more here.
Keywords: particle counter; bead based; based immunoassays; detection ... See more keywords
Electrochemiluminescence Amplification in Bead-Based Assays Induced by a Freely Diffusing Iridium(III) Complex.
Sign Up to like & getrecommendations! Published in 2023 at "ACS sensors"
DOI: 10.1021/acssensors.2c02697
Abstract: Heterogeneous electrochemiluminescence (ECL) assays employing tri-n-propylamine as a co-reactant and a tris(2,2'-bipyridine)ruthenium(II) ([Ru(bpy)3]2+) derivative as an emissive label are integral to the majority of academic and commercial applications of ECL sensing. This model system is… read more here.
Keywords: bead based; electrochemiluminescence amplification; bead; microscopy ... See more keywords
A Semiautomated Paramagnetic Bead-Based Platform for Isobaric Tag Sample Preparation.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Society for Mass Spectrometry"
DOI: 10.1021/jasms.1c00077
Abstract: The development of streamlined and high-throughput sample processing workflows is important for capitalizing on emerging advances and innovations in mass spectrometry-based applications. While the adaptation of new technologies and improved methodologies is fast paced, automation… read more here.
Keywords: sample; bead based; semiautomated paramagnetic; based platform ... See more keywords
Lifetime encoding in flow cytometry for bead-based sensing of biomolecular interaction
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-76150-x
Abstract: To demonstrate the potential of time-resolved flow cytometry (FCM) for bioanalysis, clinical diagnostics, and optically encoded bead-based assays, we performed a proof-of-principle study to detect biomolecular interactions utilizing fluorescence lifetime (LT)-encoded micron-sized polymer beads bearing… read more here.
Keywords: bead based; time; lifetime; flow cytometry ... See more keywords
Comparison of poly(styrene-divinylbenzene)-based monolithic and bead-based methodologies used in NANOFLOW LCMS for proteomic studies
Sign Up to like & getrecommendations! Published in 2018 at "Analytical Methods"
DOI: 10.1039/c8ay01264d
Abstract: Nanoflow liquid chromatography coupled with electrospray tandem mass spectrometry (nanoLC-ESI-MS/MS) is a powerful tool in proteomics analysis. The optimum conditions for preparing and the performance of a high efficiency polymeric column were compared with those… read more here.
Keywords: bead based; styrene divinylbenzene; column;
Development of a Novel Multiplex Bead-based Assay for Measuring Autoantibodies on Flow Cytometric Platform.
Sign Up to like & getrecommendations! Published in 2020 at "Immunological investigations"
DOI: 10.1080/08820139.2020.1854782
Abstract: Background: Autoantibodies (AAbs) are important biomarkers for the diagnosis of Autoimmune Diseases (ADs). The detection of AAbs performed by current methods (indirect immunofluorescence test (IIFT)/Immunoblot (dot/line)/enzyme-linked immunosorbent assay ELISA) which have limitations in terms of… read more here.
Keywords: bead based; platform; based assay; novel multiplex ... See more keywords
LED Excitation of an Imaging Cytometer for Bead-Based Immunoassay
Sign Up to like & getrecommendations! Published in 2021 at "IEEE Photonics Technology Letters"
DOI: 10.1109/lpt.2021.3070079
Abstract: We present and demonstrate a light-emitting diode (LED)-excited imaging cytometer for the detection of bead-based immunoassay samples. A broad area green LED illuminates the specimen plane using a set of aspheric lenses and an excitation… read more here.
Keywords: based immunoassay; cytometer; bead based; imaging cytometer ... See more keywords
Development of a Bead-Based Multiplex Assay for Use in Multianalyte Screening and Surveillance of HIV, Viral Hepatitis, Syphilis, and Herpes
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.02348-21
Abstract: Diagnostic assays that can simultaneously determine the presence of infection with multiple pathogens are key for diagnosis and surveillance. Current multiplex diagnostic assays are complex and often have limited availability. ABSTRACT Diagnostic assays that can… read more here.
Keywords: diagnostic assays; bead based; multiplex assay; surveillance ... See more keywords
Abstract 4117: Novel bead-based multiplex assay for the quantification of human immune checkpoint biomarkers
Sign Up to like & getrecommendations! Published in 2019 at "Immunology"
DOI: 10.1158/1538-7445.am2019-4117
Abstract: Immune checkpoint molecules are important regulators of immune activation. This regulation is critical to maintaining immune homeostasis, and is driven by a complex interplay of both co-stimulatory and inhibitory signals. These checkpoints are key to… read more here.
Keywords: checkpoint; multiplex assay; immune checkpoint; checkpoint biomarkers ... See more keywords