Synthesis of novel benzenesulfonamide bearing 1,2,3-triazole linked hydroxy-trifluoromethylpyrazolines and hydrazones as selective carbonic anhydrase isoforms IX and XII inhibitors.
Sign Up to like & getrecommendations! Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2019.01.002
Abstract: A series of twenty four hydroxy-trifluoromethylpyrazoline-carbonyl-1,2,3-triazoles and four hydrazones bearing benzenesulfonamide moieties was obtained by condensation of carboxyhydrazides with substituted 1,3-diketones. All the newly synthesized compounds were investigated as inhibitors of physiologically and pharmacologically relevant… read more here.
Keywords: synthesis novel; benzenesulfonamide bearing; triazole linked; linked hydroxy ... See more keywords
Synthesis and biological evaluation of ruthenium complexes bearing 1,2,4-triazole group as potential membrane-targeting antibacterial agents towards Staphylococcus aureus
Sign Up to like & getrecommendations! Published in 2023 at "Dalton Transactions"
DOI: 10.1039/d3dt00889d
Abstract: Bacterial infection was one of the most serious public health problems, harmful to human health and cost a lot. Nowadays, misuse and overuse of antibiotics have led to the emergence... read more here.
Keywords: ruthenium complexes; synthesis biological; biological evaluation; evaluation ruthenium ... See more keywords