Articles with "beas cells" as a keyword



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MiR‐146a regulates PM1‐induced inflammation via NF‐κB signaling pathway in BEAS‐2B cells

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Published in 2018 at "Environmental Toxicology"

DOI: 10.1002/tox.22561

Abstract: Exposure to particulate matter (PM) leads to kinds of cardiopulmonary diseases, such as asthma, COPD, arrhythmias, lung cancer, etc., which are related to PM‐induced inflammation. We have found that PM2.5 (aerodynamics diameter read more here.

Keywords: beas cells; mir 146a; induced inflammation; inflammation ... See more keywords
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Fine particle matters induce DNA damage and G2/M cell cycle arrest in human bronchial epithelial BEAS-2B cells

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Published in 2017 at "Environmental Science and Pollution Research"

DOI: 10.1007/s11356-017-0090-3

Abstract: There is compelling evidence that exposure to particulate matter (PM) is linked to lung tumorigenesis. However, there is not enough experimental evidence to support the specific mechanisms of PM2.5-induced DNA damage and cell cycle arrest… read more here.

Keywords: damage cell; dna damage; arrest; beas cells ... See more keywords
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Increased intracellular Cl- concentration by activating FAK promotes airway epithelial BEAS-2B cells proliferation and wound healing.

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Published in 2019 at "Archives of biochemistry and biophysics"

DOI: 10.1016/j.abb.2019.108225

Abstract: An increase in intracellular Cl- concentration ([Cl-]i) may be a general response of airway epithelial cells to various stimuli and may participate in some basic cellular functions. However, whether the basic functional activities of cells,… read more here.

Keywords: proliferation wound; wound healing; intracellular concentration; beas cells ... See more keywords
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Cadmium induced BEAS-2B cells apoptosis and mitochondria damage via MAPK signaling pathway.

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Published in 2021 at "Chemosphere"

DOI: 10.1016/j.chemosphere.2020.128346

Abstract: Cadmium, a heavy metal pollutant in industrial production, is found in air, water and soil, which is harmful to human health and can lead to diseases, such as asthma, lung cancer, and emphysema. In this… read more here.

Keywords: cadmium induced; cadmium; beas cells; apoptosis ... See more keywords
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Fine particulate matter exposure induces DNA damage by downregulating Rad51 expression in human bronchial epithelial Beas-2B cells in vitro.

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Published in 2020 at "Toxicology"

DOI: 10.1016/j.tox.2020.152581

Abstract: Although an accumulating body of evidence suggests that fine particulate matter (PM2.5) can cause lung injury and lung cancer, the underlying mechanisms are not yet clear. In this study, multiple endpoints associated with the cellular… read more here.

Keywords: pm2; dna damage; beas cells; exposure ... See more keywords
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Prometryn induces apoptotic cell death through cell cycle arrest and oxidative DNA damage.

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Published in 2019 at "Toxicology research"

DOI: 10.1039/c9tx00080a

Abstract: Prometryn is a slightly to moderately toxic herbicide belonging to the triazine family of herbicides, which are widely used in agriculture to control the growth of various weeds. Although many studies have shown that triazine… read more here.

Keywords: beas cells; prometryn; cell; cell cycle ... See more keywords
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Resveratrol Protects BEAS-2B Cells against Erastin-Induced Ferroptosis through the Nrf2/Keap1 Pathway

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Published in 2022 at "Planta Medica"

DOI: 10.1055/a-1923-4399

Abstract: Abstract Ferroptosis is a newly discovered type of cell death that is different from other types of cell death morphologically and biologically. It is considered to play an important role in many pulmonary diseases. Currently,… read more here.

Keywords: resveratrol; induced ferroptosis; beas cells; cells erastin ... See more keywords
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Octreotide activates autophagy to alleviate lipopolysaccharide-induced human pulmonary epithelial cell injury by inhibiting the protein kinase B (AKT)/mammalian target of rapamycin (mTOR) signaling pathway

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Published in 2021 at "Bioengineered"

DOI: 10.1080/21655979.2021.2012908

Abstract: ABSTRACT Octreotide is a synthetic octapeptide of natural somatostatin. We aimed to investigate the influence of Octreotide on lipopolysaccharide (LPS)-stimulated human pulmonary epithelial cell damage. After stimulated by LPS, BEAS-2B cells were treated with various… read more here.

Keywords: mtor signaling; cell; pulmonary epithelial; beas cells ... See more keywords
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Taxifolin improves inflammatory injury of human bronchial epithelial cells by inhibiting matrix metalloproteinase (MMP) 10 via Wnt/β-catenin pathway

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Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2021.2018384

Abstract: ABSTRACT Taxifolin (TXL), also known as dihydroquercetin, is one of the most important flavonoids prevalent across the plant kingdom. Increasing evidence has demonstrated its critical role in respiratory diseases. The present study aims to reveal… read more here.

Keywords: mmp10; wnt catenin; beas cells; catenin pathway ... See more keywords
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Screening of the differentially expressed proteins in malignant transformation of BEAS-2B cells induced by coal tar pitch extract.

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Published in 2023 at "Toxicology research"

DOI: 10.1093/toxres/tfad015

Abstract: Coal tar pitch extract (CTPE) was carcinogenic and could cause occupational lung cancer. Hence, we explored the changes of protein molecules during CTPE-induced malignant transformation (MT) of immortalized human bronchial epithelial (BEAS-2B) cells and provided… read more here.

Keywords: tar pitch; pitch extract; coal tar; beas cells ... See more keywords
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Role of LKB1 in migration and invasion of Cr(VI)-transformed human bronchial epithelial Beas-2B cells

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Published in 2018 at "Anti-Cancer Drugs"

DOI: 10.1097/cad.0000000000000638

Abstract: Hexavalent chromium [Cr(VI)] is a common human carcinogen associated with lung cancer and other pulmonary diseases as exposure to excessive Cr(VI) induces malignant transformation in human lung epithelial cells. The mechanism underlying its carcinogenicity is… read more here.

Keywords: beas cells; bgr; migration; lkb1 ... See more keywords