Comprehensive analysis of T‐cell receptor repertoires reveals antigen‐driven T‐cell clusters in patients with Behçet's syndrome
Sign Up to like & getrecommendations! Published in 2023 at "European Journal of Immunology"
DOI: 10.1002/eji.202250181
Abstract: T lymphocytes are the major components of adaptive immunity in Behçet's syndrome (BS) pathology. However, the precise mechanism of T‐cell‐induced inflammatory condition remains to be determined. We applied bulk sequencing of the T‐cell receptor (TCR)… read more here.
Keywords: analysis cell; cell; beh syndrome; cell receptor ... See more keywords
The incidence, clinical characteristics, and outcome of COVID-19 in a prospectively followed cohort of patients with Behçet’s syndrome
Sign Up to like & getrecommendations! Published in 2021 at "Rheumatology International"
DOI: 10.1007/s00296-021-05056-2
Abstract: Initial case series of small number of patients at the beginning of the pandemic reported a rather guarded prognosis for Behçet’s syndrome (BS) patients infected with SARS-CoV-2. In this prospective study, we describe the incidence,… read more here.
Keywords: incidence; cohort patients; incidence clinical; covid ... See more keywords
Update on the treatment of Behçet’s syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Internal and Emergency Medicine"
DOI: 10.1007/s11739-019-02035-1
Abstract: Behçet’s syndrome (BS) is a complex disease that shows important heterogeneity in clinical findings and physiopathology. Its treatment can be problematic as BS manifestations in different organs may respond differently to the same drug. The… read more here.
Keywords: medicine; treatment; treatment beh; beh syndrome ... See more keywords
Role of Adalimumab Biosimilar in the Treatment of Non-Anterior Uveitis Associated with Behçet’s Syndrome
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DOI: 10.1007/s40123-021-00387-6
Abstract: To evaluate the efficacy of SB5, an adalimumab biosimilar, in the management of Behçet’s syndrome (BS)-related uveitis. Data from eight BS patients (16 eyes) with active non-anterior uveitis and/or systemic uncontrolled disease or performing non-medical… read more here.
Keywords: non anterior; anterior uveitis; treatment; adalimumab biosimilar ... See more keywords
Behçet syndrome: A great imitator.
Sign Up to like & getrecommendations! Published in 2019 at "Clinics in dermatology"
DOI: 10.1016/j.clindermatol.2019.01.001
Abstract: Behçet syndrome is considered to be a multisystemic vasculitis involving the skin, mucosa, eyes, joints, nervous system, cardiovascular system, and gastrointestinal system. The exact pathogenesis of the disease is unknown, but autoimmune factors are thought… read more here.
Keywords: system; great imitator; beh syndrome; syndrome great ... See more keywords
From structure to function for the characterization of ERAP1 active site in Behçet syndrome. A novel polymorphism associated with known gene variations.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular immunology"
DOI: 10.1016/j.molimm.2019.11.005
Abstract: INTRODUCTION ERAP1 has been recently proposed as risk marker of Behçet syndrome (BS). Gene single nucleotide polymorphisms (SNPs) could affect the enzymatic activity and the conserved active site is pivotal for the aminopeptidase function. This… read more here.
Keywords: active site; site; snp; function ... See more keywords
An evaluation of apremilast for the treatment of adult patients with oral ulcers associated with Behçet’s syndrome
Sign Up to like & getrecommendations! Published in 2021 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2021.1939307
Abstract: ABSTRACT Introduction Behçet’s syndrome is a chronic, multi-system, variable vasculitis of unknown etiology that can result in significant morbidity and mortality. Mucocutaneous lesions such as oral ulcers and genital ulcers are common manifestations that can… read more here.
Keywords: apremilast treatment; evaluation apremilast; oral ulcers; genital ulcers ... See more keywords
Current pharmacological solutions for Behçet’s syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2022.2155047
Abstract: ABSTRACT Introduction Behçet’s syndrome (BS) has a heterogeneous clinical phenotype, and its clinical manifestations may respond differently to drugs commonly used to treat BS. The type, dose, and duration of immunomodulatory, immunosuppressive, and biologic agents… read more here.
Keywords: current pharmacological; solutions beh; pharmacological solutions; management ... See more keywords
Behçet's syndrome in children and young people in the United Kingdom & Republic of Ireland: a prospective epidemiological study.
Sign Up to like & getrecommendations! Published in 2021 at "Rheumatology"
DOI: 10.1093/rheumatology/keab084
Abstract: OBJECTIVES To define the incidence and prevalence of Behçet's syndrome (BS) in children and young people (CYP) up to the age of 16 years in the United Kingdom (UK) and Republic of Ireland (ROI). METHODS A… read more here.
Keywords: children young; united kingdom; syndrome children; study ... See more keywords
Frequency of AA amyloidosis has decreased in Behçet's syndrome: a retrospective study with long-term follow-up and a systematic review.
Sign Up to like & getrecommendations! Published in 2022 at "Rheumatology"
DOI: 10.1093/rheumatology/keac223
Abstract: OBJECTIVE A decline in the frequency of AA amyloidosis secondary to RA and infectious diseases has been reported. We aimed to determine the change in the frequency of AA amyloidosis in our Behçet's syndrome (BS)… read more here.
Keywords: frequency; systematic review; beh syndrome; frequency amyloidosis ... See more keywords
Behçet syndrome in children and adults: discovering similarities and differences by a comparative study.
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DOI: 10.1093/rheumatology/keac347
Abstract: OBJECTIVE Behçet's syndrome (BS) is a rare disorder with a relapsing-remitting course. Clinical variance across geographical regions and different age groups has been observed. This study matched the demographic, clinical and treatment features of adult… read more here.
Keywords: adult; syndrome children; beh syndrome; cohort ... See more keywords