Executive functioning-specific behavioral impairments in a rat model of human third trimester binge drinking implicate prefrontal-thalamo-hippocampal circuitry in Fetal Alcohol Spectrum Disorders
Sign Up to like & getrecommendations! Published in 2021 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2021.113208
Abstract: Individuals diagnosed with Fetal Alcohol Spectrum Disorders (FASD) often display behavioral impairments in executive functioning (EF). Specifically, the domains of working memory, inhibition, and set shifting are frequently impacted by prenatal alcohol exposure. Coordination between… read more here.
Keywords: third trimester; human third; model; executive functioning ... See more keywords
Thalamic Proteome Changes and Behavioral Impairments in Thiamine-deficient Rats
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DOI: 10.1016/j.neuroscience.2018.06.003
Abstract: Thiamine deficiency (TD) has been used as an experimental model in rodents to study the molecular mechanisms of neurodegeneration and its association with behavioral changes. The aims of the present study were to investigate the… read more here.
Keywords: changes behavioral; spatial cognitive; thalamic proteome; impairments thiamine ... See more keywords
Schizophrenia-Like Behavioral Impairments in Mice with Suppressed Expression of Piccolo in the Medial Prefrontal Cortex
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DOI: 10.3390/jpm11070607
Abstract: Piccolo, a presynaptic cytomatrix protein, plays a role in synaptic vesicle trafficking in the presynaptic active zone. Certain single-nucleotide polymorphisms of the Piccolo-encoding gene PCLO are reported to be associated with mental disorders. However, a… read more here.
Keywords: mpfc; medial prefrontal; piccolo; behavioral impairments ... See more keywords