Cholinergic M4 receptors are involved in morphine-induced expression of behavioral sensitization by regulating dopamine function in the nucleus accumbens of rats
Sign Up to like & getrecommendations! Published in 2019 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2018.12.009
Abstract: HIGHLIGHTSMicroinjection of LY2033298 (0.2 &mgr;g/side) into the NAcS blocked the expression of morphine‐induced behavioral sensitization.Tropicamide in the NAcS reversed the inhibitory effect of huperzine‐A on the expression of morphine‐induced behavioral sensitization.SKF38393 in the NAcS reversed… read more here.
Keywords: morphine; expression behavioral; morphine induced; behavioral sensitization ... See more keywords
Glutathione peroxidase-1 knockout potentiates behavioral sensitization induced by cocaine in mice via σ-1 receptor-mediated ERK signaling: A comparison with the case of glutathione peroxidase-1 overexpressing transgenic mice
Sign Up to like & getrecommendations! Published in 2020 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2020.08.011
Abstract: We demonstrated that the gene of glutathione peroxidase-1 (GPx-1), a major antioxidant enzyme, is a potential protectant against the neurotoxicity and conditioned place preference induced by cocaine. Because the sigma (σ)-1 receptor is implicated in… read more here.
Keywords: gpx; behavioral sensitization; mice; receptor ... See more keywords
Involvement of dopamine D2 receptor in a single methamphetamine-induced behavioral sensitization in C57BL/6J mice
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2018.02.067
Abstract: A single exposure to drugs of abuse is sufficient to induce behavioral sensitization, which is a form of long-lasting neuroplasticity. Dopamine D2 receptors are the main receptor for antipsychotic drugs, but little is known about… read more here.
Keywords: methamphetamine; methamphetamine induced; single methamphetamine; behavioral sensitization ... See more keywords
Environmental novelty modulates the induction and expression of single injection-induced behavioral sensitization to morphine
Sign Up to like & getrecommendations! Published in 2018 at "Pharmacology Biochemistry and Behavior"
DOI: 10.1016/j.pbb.2018.07.006
Abstract: ABSTRACT Opioid addiction is a growing public health problem, being currently considered an epidemic in the United States. Investigating the behavioral effects of opioids and the factors influencing their development becomes of major importance. In… read more here.
Keywords: phase; expression; behavioral sensitization; induction ... See more keywords
Repeated nicotine vapor inhalation induces behavioral sensitization in male and female C57BL/6 mice
Sign Up to like & getrecommendations! Published in 2020 at "Behavioural Pharmacology"
DOI: 10.1097/fbp.0000000000000562
Abstract: Electronic cigarette use has significantly increased over the past decade. However, there is limited preclinical research on the behavioral and abuse-related effects of nicotine vapor inhalation in rodents. The present study evaluates the effects of… read more here.
Keywords: nicotine vapor; vapor inhalation; behavioral sensitization;
Behavioral sensitization and cellular responses to psychostimulants are reduced in D2R knockout mice
Sign Up to like & getrecommendations! Published in 2019 at "Addiction Biology"
DOI: 10.1111/adb.12840
Abstract: Repeated cocaine exposure causes long‐lasting neuroadaptations that involve alterations in cellular signaling and gene expression mediated by dopamine in different brain regions, such as the striatum. Previous studies have pointed out to the dopamine D1… read more here.
Keywords: knockout mice; d2r; expression; behavioral sensitization ... See more keywords
Toluene-Induced Behavioral Sensitization is Attenuated by Voluntary Physical Exercise and Social Interaction
Sign Up to like & getrecommendations! Published in 2023 at "Adaptive Behavior"
DOI: 10.1177/10597123231178941
Abstract: Toluene-based inhalants found in some common products, such as paint thinner or glues, may be used to induce intoxication. Though addiction may be one of its most detrimental consequences, treatment options are insufficient or limited.… read more here.
Keywords: housing; toluene induced; sensitization; behavioral sensitization ... See more keywords
Behavioral sensitization induced by methamphetamine causes differential alterations in gene expression and histone acetylation of the prefrontal cortex in rats
Sign Up to like & getrecommendations! Published in 2021 at "BMC Neuroscience"
DOI: 10.1186/s12868-021-00616-5
Abstract: Background Methamphetamine (METH) is one of the most widely abused illicit substances worldwide; unfortunately, its addiction mechanism remains unclear. Based on accumulating evidence, changes in gene expression and chromatin modifications might be related to the… read more here.
Keywords: gene expression; histone acetylation; acetylation; behavioral sensitization ... See more keywords
Ethanol-Induced Behavioral Sensitization Alters the Synaptic Transcriptome and Exon Utilization in DBA/2J Mice
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2018.00402
Abstract: Alcoholism is a complex behavioral disorder characterized by loss of control in limiting intake, and progressive compulsion to seek and consume ethanol. Prior studies have suggested that the characteristic behaviors associated with escalation of drug… read more here.
Keywords: synaptic transcriptome; ethanol; behavioral sensitization; ethanol induced ... See more keywords
Maternal Methamphetamine Exposure Influences Behavioral Sensitization and Nucleus Accumbens DNA Methylation in Subsequent Generation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.940798
Abstract: The deleterious effects of methamphetamine (METH) exposure extend beyond abusers, and may potentially impact the vulnerability of their offspring in developing addictive behaviors. Epigenetic signatures have been implicated in addiction, yet the characteristics to identify… read more here.
Keywords: meth exposure; meth; behavioral sensitization; exposure ... See more keywords
Mitigating Effects of Liriope platyphylla on Nicotine-Induced Behavioral Sensitization and Quality Control of Compounds
Sign Up to like & getrecommendations! Published in 2020 at "Brain Sciences"
DOI: 10.3390/brainsci10090654
Abstract: In this study we investigated the mitigating effects of Liriope platyphylla Wang et Tang extract on behavioral sensitization and the quantification of its major compounds. The extract of L. platyphylla reduces the expression of tyrosine… read more here.
Keywords: nicotine induced; control; behavioral sensitization; quality control ... See more keywords