Behaviour of Tetrabenazine in Acid Medium: Reassessment and Impact on Formulation
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DOI: 10.3390/pharmaceutics11010044
Abstract: Thorough studies of previous analytical stress data of tetrabenazine, a dopamine depleting agent, showed a potential susceptibility to acidic conditions. Hence, the behavior of tetrabenazine acidic solutions was studied by LC-MS and NMR spectroscopy. Reverse-phase… read more here.
Keywords: tetrabenazine; tetrabenazine acid; behaviour tetrabenazine; acid medium ... See more keywords